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Gamme d'année
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Rev. méd. Chile ; 136(8): 976-980, ago. 2008. graf, tab
Article Dans Espagnol | LILACS | ID: lil-495795

Résumé

Background: Previous reports describe 30-40 percent of small intestine bacterial overgrowth (SIBO) in patients with chronic pancreatitis (CP), SIBO is a cause of persistent symptoms in this group of patients even when they are treated with pancreatic enzymes. Aim: To asses the frequency of SIBO in patients with CP. Patients and methods: We studied 14 patients with CP using an hydrogen breath test with lactulose to detect SIBO, a nonabsorbable carbohydrate, whose results are not influenced by the presence of exocrine insufficiency. Main symptoms and signs were bloating in 9 (64 percent), recurrent abdominal pain in 8 (57 percent), intermittent diarrhea in 5 (36 percent) and steatorrhea in 5 (36 percent). At the same time we studied a healthy control group paired by age and sex. Results: SIBO was present in 13 of 14 patients with CP (92 percent) and in 1 of 14 controls (p<0.001). The only patient with CP and without SIBO was recently diagnosed and had minimal morphologic alterations in computed tomography and endoscopic pancreatography Conclusions: SIBO is common in CP and may be responsible for persistent symptoms. Proper diagnosis and treatment could alleviate symptoms and improve quality of life.


Sujets)
Adulte , Sujet âgé , Femelle , Humains , Mâle , Adulte d'âge moyen , Jeune adulte , Bactéries/croissance et développement , Infections bactériennes/diagnostic , Intestin grêle/microbiologie , Lactulose , Pancréatite chronique/microbiologie , Bactéries/isolement et purification , Tests d'analyse de l'haleine , Études cas-témoins , Chili , Diarrhée/microbiologie , Hydrates de carbone alimentaires/métabolisme , Insuffisance pancréatique exocrine/diagnostic , Insuffisance pancréatique exocrine/microbiologie , Hydrogène/analyse , Pancréatite chronique/diagnostic , Jeune adulte
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