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Braz. j. med. biol. res ; 24(1): 21-7, jan.-mar. 1991. ilus
Article Dans Anglais | LILACS | ID: lil-99576

Résumé

The molecular weight and the electrofocusing profile of human amniotic membrane interferon (IFN-AM) were determined. When submitted to gel filtration, IFN-AM showed a single 26-28 kDa component; in polyacrylamide gel electrophoresis one component of 19,500. In electrofocusing, IFN-AM displayed a terogeneity was reduced by previous treatment of IFN-AM with neuraminidase. IFN-AMis a siaglycoprotein similarto human beta IFN in terms of antigenicity but different from it in electrofocusing profile


Sujets)
Humains , Membranes extraembryonnaires/métabolisme , Interférons/composition chimique , Placenta/analyse , Chromatographie sur gel , Électrophorèse sur gel de polyacrylamide , Focalisation isoélectrique , Masse moléculaire
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