Cutaneous manifestations of diabetes mellitus

Diabetes isa common disease with a variety of skin manifestations encountered by dermatologists, Skin and diabetes may be linked by association [e.g. necrobiosis lipoidica]; infections [bacterial, viral or fungal]; diabetic complications [e.g. neuropathic ulcers or treatment reactions]. The skin manifestations of diabetes affect up to two thirds of patients both type 1 and II diabetes mellitus. Cutanebus manifestations of diabetes occur because of the microvascular complications of diabetes, impaired wound healing, and other yet undetermined mechanisms. The aim of the present study was to look for major skin findings in patients with diabetes mellitus and to see their clinical correlation. All patients attending the diabetic clinic during a period of Qne year from July, 2002 to June, 2003 were examined in detail for cutaneous manifestations of the disease. 162 patients, 92 females and 70 males, were enrolled. The overall prevalence of cutaneous manifestations was 81.5% [80% in type I and 83.4% in type II diabetics]. These manifestations were microvascular [n73], neurological [n6 1], infections [n46], iatrogenic [n=7] and miscellaneous [n=184]. Cutaneous manifestations are quite frequent in both types of diabetics. A number of new findings were observed

Cutaneous manifestations of chronic liver disease

Hepatobiliary diseases are frequently associated with abnormalities of the skin, nails and hair. This study was undertaken to determine the cutaneous manifestations of chronic liver disease [CLD] and particular pattern associated with aetiology of disease. Patients suffering from chronic liver disease of any aetiology presenting to department of gastroenterology Hayatabad Medical Complex, Peshawar from 1st December 2004 to 30th April 2005 were enrolled in the study. All the relevant details regarding history and clinical examination were recorded on a specially designed pro forma. A total of fifty patients, 32 males and 18 females were included. Thirty [60%] patients were suffering from chronic hepatitis C virus infection, 14 patients were suffering from Chronic hepatitis B virus infection and 2 patients each were suffering from primary biliary cirrhosis and Wilson's disease. In two cases the aetiology could not be ascertained. Different manifestations included pigmentation [82%], Terry's nails [80%], xerosis and excoriations [72%], nonscarring hair loss from axilla and pubic region [64%], and spider naevi and palmar erythema [36%]. Lichen planus was seen in 4%, vitiligo and hepatocutaneous syndrome in [2%] of patients each. Cutaneous manifestations in chronic liver disease are non-specific and do not point towards specific aetiology. Physicians caring for patients with chronic liver disease should pay attention to its multisystemic nature

Food and skin

Food is essential to keep our body healthy and in perfect harmony. The relationship between food and skin is diverse. Food can help to cure certain skin disorders but it can also trigger or aggravate various other dermatoses. This article highlights the role of different food items in dermatological disorders under various headings

Complicaciones cutaneas de la terapia inmunosupresora: estudio en transplantados renales / Cutaneous complications of immunosupressive therapy: study in patients with kidney transplantation

Se presenta la expeirncia dermatologica obtenida durante el seguimiento prospectivo de 114 pacientes con trasplante renal, atendidos en el Hospital Universitario San Vicente de Paul, de Medellin; su evolucion post-trasplante fluctuaba entre 2 meses y 13 anos y el seguimiento dermatologico fue por dos anos. Se encontro un numero elevado de maniefestaciones cutaneas; las mas frecuentes fueron: acne, micosis, hirsutismo y xerosis; no se hallaron lesiones malignas. No hubo asociacion de las manifestaciones cutaneas con la edad del paciente, el tipo de donante o el esquema inmunosupresor. Dada la alta frecuencia de patologia cutanea se sugiere que estos pacientes sean educados adecuadamente sobre este aspecto y examinados periodicamente con el fin de detectar y manejar a tiempo sus problemas dermatologicos benignos o potencialmente malignos