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Indian J Exp Biol ; 1991 Mar; 29(3): 226-9
Article Dans Anglais | IMSEAR | ID: sea-57045

Résumé

Acute single dose (ip) administration of two rare earth elements like lanthanum chloride (250 mg/kg body wt) and neodymium chloride (200 mg/kg body wt) to chicks have been found to reduce the activity of certain erythrocyte membrane bound enzymes, viz. acetylcholinesterase, NADH dehydrogenase, Mg(2+)-ATPase, p-nitrophenyl phosphatase. Erythrocyte membrane bound glycosidases e.g. beta-D-glucosidase, beta-D-galactosidase and beta-D-glucuronidase were also reduced. Other components such as cholesterol and phospholipid residues were reduced but their ratio (cholesterol/phospholipid) remaining unchanged. Membrane sulfhydryl groups were also significantly inhibited by these rare earth elements.


Sujets)
Animaux , Poulets , Membrane érythrocytaire/effets des médicaments et des substances chimiques , Glycosidases/sang , Lanthane/toxicité , Mâle , Lipides membranaires/sang , Néodyme/toxicité
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