Effect of monosodium glutamate on the nerve cells of adult male albino rat. histological study

Monosodium glutamate [MSG] is one of the food additives which modify the flavor of food. This study was done to detect the possible effects of monosodium glutamate in its recommended and high doses on both types of nerve cells motor and sensory. 30 adult male albino rats were used in this study. They were classified into the following groups: Group I control group. Group II included animals which received the recommended dose of MSG 4 mg/gm of body weight/day orally for one month. Half of these animals were sacrificed after one month from MSG administration, while the rest of the animals were sacrificed 2 months after stoppage of MSG administration. Group III, in which the animals were given double dose of MSG 8 mg/gm of body weight/day orally for one month, 5 animals were sacrificed after one month from MSG administration. The other animals were sacrificed 2 months after stoppage of MSG administration

Visualization of neurons forming the obturator nerve in albino rat

To localize and estimate the size, number and segmental distribution of motor, dorsal root ganglion [DRG] and postganglionic sympathetic [PSN] neurons whose axons form the obturator nerve in albino rat. Setting: Department of Anatomy, Basic Medical Sciences Institute, Jinnah Postgraduate Medical Centre, Karachi. Subjects: Male, adult albino rats of Charles River strain. Main outcome measures: Horseradish peroxidase [HRP] method of tracing neurons by injecting 25-30% HRP solution into the muscles supplied by the obturator nerve. The motoneurons extended between L2 and L4 segments of the spinal cord, appeared as groups of neurons occupying anterolateral, posterolateral and central groups. The labelled sensory neurons located in L2-L4 ipsilateral dorsal root ganglia were densely populated in L3 DRG without any somatotopic organization. Ike sympathetic neurons were labelled in L2-L4 sympathetic ganglia with heavy labelling in The. The somal diameters of the motoneurons ranged between 10 and 50 micro m with majority having somal diameters greater than 25 micro m. The size spectrum of sensory neurons measured between 12 and 50 micro m and that of sympathetic ganglion cells between 10 and 38 micro m

Estudio de las neuronas del núcleo supraóptico del hipotálamo en ambos hemisferios de ratas después del parto / Study of the neurons of the hypothalamic supraoptic nucleus in both hemispheres in rats after delivery

Se estudiaron las características morfológicas (volumen nuclear y cantidad de material neurosecretor presentes en el ciplasma celular) que son índices del estado funcional de las neuronas del núcleo supraóptico del hipotálamo, en ambos hemisferios de ratas después del parto. Se compararon los resultados de ambos hemisferios mediante la prueba de la t de Student, que indica asimetría hemisférica en esta área del sistema nervioso central. El volumen nuclear es mayor y la cantidad de material neurosecretor más escaso en las neuronas del núcleo supraóptico del hemisferio izquierdo, lo que indica un aumento de la síntesis y liberación de las neurohormonas oxitocina y principalmente vasopresina