1.
Indian J Exp Biol
; 1991 Dec; 29(12): 1145-6
Article
de Anglais
| IMSEAR
| ID: sea-59921
RÉSUMÉ
Daily oral administration of antiestrogen centchroman at 6.25, 12.5 and 25 mg/kg doses to adult female rhesus monkeys continuously for one year caused no significant effect on their total pituitary gonadotrophin content as evidenced by an almost similar extent of uterine weight gain, premature opening of vagina and cornification of vaginal epithelium in immature female mice treated with pituitary homogenates from control and centchroman treated monkeys.