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Braz. j. med. biol. res ; 38(8): 1203-1208, Aug. 2005. ilus
Article Dans Anglais | LILACS | ID: lil-405521

Résumé

Many cellular proteins are bound to the surfaces of membranes and participate in various cell signaling responses. Interactions between this group of proteins are in part controlled by the membrane surface to which the proteins are bound. This review focuses on the effects of pressure on membrane-associated proteins. Initially, the effect of pressure on membrane surfaces and how pressure may perturb the membrane binding of proteins is discussed. Next, the effect of pressure on the activity and lateral association of proteins is considered. We then discuss how pressure can be used to gain insight into these types of proteins.


Sujets)
Humains , Pression hydrostatique , Protéines membranaires/métabolisme , Isoenzymes/composition chimique , Isoenzymes/métabolisme , Double couche lipidique/composition chimique , Double couche lipidique/métabolisme , Protéines membranaires/composition chimique , Phospholipase C delta , Liaison aux protéines , Électricité statique , Type C Phospholipases/composition chimique , Type C Phospholipases/métabolisme
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