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Gamme d'année
2.
Braz. j. med. biol. res ; 23(9): 919-22, 1990. ilus
Article Dans Anglais | LILACS | ID: lil-92455

Résumé

The medullary raphe are involved in the control of sympathetic activity during desynchonized sleep and in the modulation of nocicepotive sensory inpts. To determine the particpation cholinergic and opiate mechanisms in the control of sympathetic activity, we microinjected eserine, morphine and naloxone into the nucleus raphe obscurus (NRO) of urethane-anesthetized rats. Arterial blood pressure (BP) and renal nerve activity (RN) were recorded. Eserine and morphine induced significant reductions of RN and BP, while naloxone had no effect. It is suggested that cholinergic and opiate mechanisms particpate in the control of sympathetic activity by th NRO


Sujets)
Rats , Animaux , Mâle , Morphine/pharmacologie , Naloxone/pharmacologie , Noyaux du raphé/physiologie , Parasympathomimétiques , Physostigmine/pharmacologie , Système nerveux sympathique/physiologie , Pression sanguine/effets des médicaments et des substances chimiques , Microinjections , Morphine/administration et posologie , Naloxone/administration et posologie , Physostigmine/administration et posologie , Rat Wistar
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