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Indian J Pathol Microbiol ; 2007 Oct; 50(4): 917-9
Article Dans Anglais | IMSEAR | ID: sea-73593

Résumé

Non-hematopoietic malignancies infiltrating bone marrow have always been a source of erroneous diagnosis. Among these, the small round cell tumors like neuroblastomas and rhabdomyosarcomas mimick the hematopoietic blasts. Several case reports of rhabdomyosarcoma mimicking acute leukemia, clinically and morphologically at presentation have been reported in the literature. To the best of our knowledge such an entity has not been reported in Indian literature. We report here one such case of alveolar rhabdomyosarcoma masquerading as acute leukemia. A thorough clinical examination with high degree of suspicion on bone marrow morphology and judicious use of appropriate immunohistochemistry markers will solve many of these cases.


Sujets)
Adolescent , Antigènes CD30/analyse , Antigènes CD45/analyse , Moelle osseuse/anatomopathologie , Desmine/analyse , Diagnostic différentiel , Humains , Immunohistochimie , Mâle , Protéine MyoD/analyse , Myogénine/analyse , Myeloperoxidase/analyse , Enolase/analyse , Rhabdomyosarcome alvéolaire/composition chimique , Marqueurs biologiques tumoraux/analyse
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