Esquistosomiasis mansonica riesgo en la Cuenca del Plata / Esquistosomiasis mansonica risk in the Cuenca of the Plata

Visto el avance de 1000 km. de la esquistosomíasis en el cuenca del Plata, en los últimos años, el presente trabajo tiene el objetivo de efectuar un diagnostíco de situación y propuesta de soluciones de tan grave endemia. Con un impacto socioeconomic tan importante. En nuestro país ya hay registros de casos humanos en la provincia de Misiones.

Aspects of the granulomatous reaction in the liver of mice infected and reinfected with two different geographical strains of schistosoma mansoni

In this study, which was undertaken in relation to the histopathologic behavior of two different strains (LE - Belo Horizonte, MG and SJ - Sao José dos Campos, SP) in infections and reinfections (homologous or heterologous) with Schistosoma mansoni, the authors confirmed a more accentuated pathogenicity of the SJ strain. All the reinfections showed the presence of typical granulomas of the acute phase, when performed either with the same strain (homologous) or with a different strain (heterologous) of the parasite of the primo infection. The possible mechanisms responsible for reactivation of the immunopathologic response in reinfections are discussed.