Résumé
No abstract available.
Sujets)
Femelle , Humains , Adulte d'âge moyen , Chambre antérieure du bulbe oculaire/effets des médicaments et des substances chimiques , Maladies de l'oeil/induit chimiquement , Glucocorticoïdes/administration et posologie , Injections oculaires , Pose d'implant intraoculaire , Phacoémulsification/effets indésirables , Rupture de la capsule postérieure du cristallin/diagnostic , Prolapsus , Suppuration/induit chimiquement , Triamcinolone acétonide/administration et posologie , Vitrectomie , Corps vitréRésumé
We report a case of 61-yr-old man with stable psoriasis who progressively developed generalized pustular eruption, erythroderma, fever, and hepatic dysfunction following oral terbinafine. Skin biopsy was compatible with pustular psoriasis. After discontinuation of terbinafine and initiating topical corticosteroid and calcipotriol combination with narrow band ultraviolet B therapy, patient's condition slowly improved until complete remission was reached 2 weeks later. The diagnosis of generalized pustular psoriasis (GPP) induced by oral terbinafine was made. To our knowledge, this is the first report of GPP accompanied by hepatic dysfunction associated with oral terbinafine therapy.
Sujets)
Adulte d'âge moyen , Mâle , Humains , Suppuration/induit chimiquement , Psoriasis/induit chimiquement , Naphtalènes/effets indésirables , Maladies du foie/induit chimiquement , Antifongiques/effets indésirables , Administration par voie oraleRésumé
OBJECTIVES: Outbreaks are known to occur after Bacillus Calmette Guerin (BCG) vaccination. An outbreak of suppurative lymphadenitis in 18 infants, following BCG vaccination is reported from Sikkim, with incidence of 8.6%. The outbreak occurred after a change of vaccine. METHODS: In a prospective study the cases of suppurative lymphadenitis were diagnosed by needle aspiration cytology and culture of the material aspirated and managed only with repeated needle aspiration and no antitubercular treatment was given. RESULTS: Cytomorphology revealed necrosis alone in 66.6% and necrotizing granulomas in 22.2%. Acid and alcohol fast bacilli were detected in 77.7% cases. Mycobacterium bovis was isolated in eight cases. One case of staphylococcal suppurative lymphadenitis was detected. Sixteen cases were managed with weekly aspiration with mean period of resolution in eight weeks. CONCLUSIONS: Needle aspiration is useful in the diagnosis and effective in the management of these cases. No antitubercular treatment is desired and required in the cases of suppurative lymphadenitis following BCG vaccination.