Multiple cutaneous telangiectasias after the use of trastuzumab: a case report

We aim to report a particular case of cutaneous telangiectasias on the arms after immunotherapy with trastuzumab plus paclitaxel to treat breast cancer. New oncology therapies reflect a major advance in cancer treatment. They greatly increase survival; however, they still cause certain adverse cutaneous events that should be taken into account for their proper management.

Epidemiologic study of 112 osteosarcomas in Chiang Mai University Hospital, Thailand.

OBJECTIVE: To summarize the epidemiologic features of osteosarcoma. MATERIAL AND METHOD: One hundred and twelve cases of osteosarcoma were collected retrospectively from the Pathology Department of the Chiang Mai University Hospital, Thailand between 1995 and 2005. RESULTS: From the present study, there were 14 cases in average, annually, since 2002. Seventy-seven percent of cases were from the upper north Thailand, the region serviced by Chiang Mai University Hospital. The male:female ratio was 1.3:1 and 86% of cases occurred within the first three decades of life. The majority of cancer was found in the long bones (83%) and the majority of lesion was around the knee (68%). Conventional and telangiectatic osteosarcoma accounted for 85% and 8% of cases, respectively. CONCLUSION: The authors have summarized some epidemiologic features of osteosarcoma. The authors found the relatively high frequency of telangiectatic osteosarcoma around the upper part of north Thailand These results give an initial picture to the national health provider section for planning personnel, medical and supportive equipment, and funding for the care of osteosarcoma patients. Nationwide co-operation in registering osteosarcoma patients would provide more complete data on this tumor in Thailand and promote the establishment of standardized treatment protocols.

Presentación de pseudotumores de origen mesenquimáticos de cavidad bucal según sexo, edad y localización / Presentation of oral pseudotumors of mesenchimatic origin, according to sex, age and localization

El objetivo del trabajo consiste en resaltar la frecuencia de presentación y caracterización de los pseudotumores mesenquimáticos en la cavidad bucal.Se analizó la presentación de pseudotumores de origen mesenquimáticos dentro de la cavidad bucal, observando la histopatología y teniendo en cuenta las variables sexo, edad y localización. Se realizó una investigación retrospectiva de los archivos del laboratorio de Anatomía Patológica Dr. Walter A. Alsina de la FOUNNE, revisando los protocolos de biopsias y preparados histopatológicos informados durante el año 2005. Del total de 189 casos, se separaron 59 correspondientes a los Pseudotumores de origen mesenquimáticos (37 por ciento). Dentro de este grupo y teniendo en cuenta el orden de frecuencia se observó: Hiperplasia Fibrosa 68 por ciento; Granuloma Telangiectásico 20 por ciento y Granuloma Gigantocelular Periférico 12 por ciento. La edad media de presentación de los pseudotumores mesenquimáticos bucales en la muestra estudiada fue de 46 años y la localización más frecuente, encía. La diferencia entre sexos no es significativa.