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2.
Article Dans Anglais | LILACS, CUMED | ID: biblio-1508227

Résumé

Introducción: Debido a la necesidad de un diagnóstico precoz de los trastornos neurodegenerativos, se ha intentado armonizar los criterios diagnósticos mediante métodos morfométricos basados en técnicas de neuroimagen, pero aún no se han obtenido resultados concluyentes. Objetivo: Determinar el volumen ventricular debido a su amplio uso como marcador de atrofia cerebral e identificar el efecto del sexo sobre estas estructuras, según el tipo de cráneo, estimado a partir de técnicas de imagen de tomografía computarizada multicorte. Métodos: Se desarrolló un estudio observacional y descriptivo en 30 sujetos con funciones neurocognitivas y exploración neuropsiquiátrica normales, con edades comprendidas entre 45 y 54 años, a los que se les realizó una tomografía computarizada multicorte simple de cráneo. Se utilizó un método de segmentación de imágenes basado en la homogeneidad. Resultados: Los volúmenes ventriculares mostraron una correlación significativa y positiva entre ellos, excepto entre el tercer y cuarto ventrículo y el tercero y el volumen ventricular derecho. Los estadísticos del modelo lineal multivariante aplicado mostraron que sólo eran significativos en función del sexo y del tipo de cráneo. No se encontraron diferencias significativas con respecto al sexo en ningún volumen, excepto en el tercer ventrículo (p= 0,01). Lo mismo ocurrió por tipo de cráneo (p= 0,005). Conclusiones: El método de morfometría del sistema ventricular encefálico a partir de imágenes de Tomografía Computarizada / Segmentación por homogeneidad, permitió cuantificar los cambios volumétricos cerebrales asociados al envejecimiento normal y puede ser utilizado como biomarcador de la relación entre la estructura cerebral y las funciones cognitivas(AU)


Introduction: Due to the need for an early diagnosis of neurodegenerative disorders, attempts have been made to harmonize diagnostic criteria using morphometric methods based on neuroimaging techniques, but conclusive results have not yet been obtained. Objective: To determine the ventricular volume due to its wide use as a marker of cerebral atrophy and to identify the effect of sex on these structures, according to the type of skull, estimated from multislice computed tomography imaging techniques. Methods: An observational and descriptive study was developed in 30 subjects with normal neurocognitive functions and neuropsychiatric examination, aged between 45 and 54 years, who underwent a simple multislice CT scan of the skull. An image segmentation method based on homogeneity was used. Results: The ventricular volumes showed a significant and positive correlation between them, except between the third and fourth ventricles and the third and the right ventricular volume. The statistics in the multivariate linear model applied showed that they were only significant in terms of sex and type of skull. No significant differences were found regarding sex in any volume except in the third ventricle (p= 0.01). The same occurred by type of skull (p= 0.005). Conclusions: The morphometry method of the encephalic ventricular system from Computed Tomography images / Segmentation by homogeneity, allowed to quantify the cerebral volumetric changes associated with normal aging and can be used as a biomarker of the relationship between brain structure and cognitive functions(AU)


Sujets)
Humains , Adulte d'âge moyen , Ventricules cérébraux/imagerie diagnostique , Anthropométrie/méthodes , Titrimétrie/méthodes , Cognition , Tomodensitométrie multidétecteurs/méthodes , Neuroimagerie/méthodes , Épidémiologie Descriptive , Étude d'observation
3.
Int. j. morphol ; 40(5): 1308-1320, 2022. ilus, tab
Article Dans Anglais | LILACS | ID: biblio-1405271

Résumé

SUMMARY: To establish an unprovable diagnostic indicative index reference for ultrasound examination of the fetal cerebral ventricles, based on the morphological characteristics throughout fetal nervous system development. Key ultrasonic morphological indicators of fetal ventricular development, which includes frontal horn width (FHW), occipital horn width (OHW), width of 3rd ventricle, cavity of septum pellucidum (CSP), width and length of 4th ventricle and thalamo-occipital distance (TOD) had been measured and analyzed collectively. All data of the indicators was collected on singleton pregnant woman between 16-39 weeks of gestational age (GA), between November 2017 and June 2021 at the Second Hospital of Dalian Medical University. A total of 235 pregnant women were enrolled in the cross section study; another 36 pregnant women voluntarily joined a timeline-tracking follow-up study (cohort study) under the same examining criteria. A decrease of FHW and OHW of the lateral ventricles was observed as GA increased; while dimensional values of TOD, 3rd ventricle, CSP, as well as 4th ventricle increased with GA. Most of these indicators showed an enhanced variation tendency within a certain period of GA. Moreover, values of FHW and TOD showed asymmetry of the two hemispheres within the whole GA. Our findings revealed the morphological regularity of fetal ventricular development, which would instructively enhance the relative clinical ultrasound diagnosis; moreover, TOD also showed regularly changes as GA increased, suggesting that TOD should be considered as an additional routine ultrasonic indicator for fetal ventricular development.


RESUMEN: El objetivo del estudio fue establecer un índice de referencia indicativo diagnóstico no demostrable para el examen ecográfico de los ventrículos cerebrales fetales, basado en las características morfológicas a lo largo del desarrollo del sistema nervioso fetal. Indicadores morfológicos ultrasónicos clave del desarrollo ventricular fetal, que incluyen el ancho del cuerno frontal (FHW), el ancho del cuerno occipital (OHW), el ancho del tercer ventrículo, la cavidad del septo pelúcido (CSP), el ancho y el largo del cuarto ventrículo y la distancia tálamo-occipital (TOD) fueron medidos y analizados conjuntamente. Todos los datos de los indicadores se recopilaron en mujeres embarazadas de un solo feto entre 16 y 39 semanas de edad gestacional (EG), entre noviembre de 2017 y junio de 2021 en el Segundo Hospital de la Universidad Médica de Dalian. Un total de 235 mujeres embarazadas se inscribieron en el estudio transversal; otras 36 mujeres embarazadas se unieron voluntariamente a un estudio de seguimiento de línea de tiempo (estudio de cohorte) bajo los mismos criterios de examen. Se observó una disminución de FHW y OHW de los ventrículos laterales a medida que aumentaba la GA; mientras que los valores dimensionales de TOD, tercer ventrículo, CSP y cuarto ventrículo aumentaron con GA. La mayoría de estos indicadores mostraron una tendencia de variación mejorada dentro de un cierto período de GA. Además, los valores de FHW y TOD mostraron asimetría de los dos hemisferios dentro de toda la AG. Nuestros hallazgos revelaron la regularidad morfológica del desarrollo ventricular fetal, lo que mejoraría de manera instructiva el diagnóstico clínico de ultrasonido relativo; además, TOD también mostró cambios regulares a medida que aumentaba la GA, lo que sugiere que TOD debe considerarse como un indicador ultrasónico de rutina adicional para el desarrollo ventricular fetal.


Sujets)
Humains , Femelle , Grossesse , Ventricules cérébraux/croissance et développement , Ventricules cérébraux/imagerie diagnostique , Échographie prénatale
4.
Rev. argent. neurocir ; 35(2): 145-149, jun. 2021. ilus
Article Dans Espagnol | LILACS, BINACIS | ID: biblio-1398279

Résumé

El abordaje interhemisférico contralateral es una variante del abordaje interhemisférico transcalloso que permite optimizar el acceso a lesiones ubicadas en los ventrículos laterales o en sus paredes. La planificación del ángulo de entrada mediante neuronavegador nos permitió el manejo de un Cavernoma ubicado sobre el núcleo caudado e inmediato a la cápsula interna sin realizar callosotomía convencional ni comprometer las estructuras sensibles adyacentes.


Contralateral interhemispheric approach is a variant of the well-know interhemispheric transcallosal approach that allows to optimize the lateral wall ventricle lesions management. Neuronavigation planning allowed us to deal with a caudate nucleus cavernoma contiguous to internal capsule without conventional callosotomy and additional damage neither.


Sujets)
Cerveau , Ventricules cérébraux , Capsule interne , Neuronavigation
5.
Arq. bras. neurocir ; 40(2): 146-151, 15/06/2021.
Article Dans Anglais | LILACS | ID: biblio-1362220

Résumé

Purpose Experimental models might help understand the pathophysiology of neurocysticercosis-associated hydrocephalus. The present study aimed to compare the extent of hydrocephalus and tissue damage in rats with subarachnoid inoculation of different concentrations of Taenia crassiceps cyst proteins. Methods Sixty young rats were divided into two groups: low- and high-concentration groups. The animals in the low concentration group received 0.02ml of 2.4mg/ml T. crassiceps cyst proteins while those in the high concentration group received 0.02 ml of 11.6mg/ml T. crassiceps cyst proteins. The animals underwent magnetic resonance imaging at 1, 3, and 6 months postinoculation to assess the ventricle volume. Morphological assessment was performed at the end of the observation period. Results Repeated measures of ventricle volumes at 1, 3, and 6 months showed progressive enlargement of the ventricles. At 1 and 3 months, we observed no differences in ventricle volumes between the 2 groups. However, at 6 months, the ventricles were larger in the high concentration group (median » 3.86mm3, range: 2.37­12.68) compared with the low concentration group (median » 2.00mm3, range: 0.37­11.57), p » 0.003. The morphological assessment revealed a few inflammatory features in both groups. However, the density of oligodendrocytes and neurons within the periventricular region was lower in the high concentration group (5.18 versus 9.72 for oligodendrocytes and 15.69 versus 21.00 for neurons; p < 0.001 for both). Conclusion Our results suggest that, in rats, a higher concentration of T. crassiceps cyst proteins in the subarachnoid space could induce ventricle enlargement and reduce the number of neurons within the periventricular area.


Sujets)
Animaux , Rats , Ventricules cérébraux/physiopathologie , Neurocysticercose/anatomopathologie , Hydrocéphalie/parasitologie , Antigènes d'helminthe , Espace sous-arachnoïdien/physiopathologie , Taenia , Imagerie par résonance magnétique/méthodes , Rat Wistar , Statistique non paramétrique , Infections parasitaires du système nerveux central , Interactions hôte-parasite , Hydrocéphalie/physiopathologie
8.
Int. j. morphol ; 37(2): 554-560, June 2019. tab, graf
Article Dans Anglais | LILACS | ID: biblio-1002258

Résumé

The aim of this study was to determine the normal values of brain ventricles and indices in healthy subjects in our population using magnetic resonance imaging (MRI) and to reveal sex and age related differences. The MRI of two hundred-sixty-five healthy individuals aged between eighteen and eighty-seven years were examined and the midsagittal and axial images were used for measurements. The measurements were performed from MRI on a Workstation. The following mean values of brain ventricles and indices were observed; frontal horn width (FHW) (33.14 mm); third (3rd) ventricle width (TVW) (3.37 mm); fourth ventricle anteroposterior width (FVWAP) (9.93 mm); fourth ventricle transverse width (FVWT) (12.40 mm); and the maximum transverse inner diameter of the skull (TIDS) (128.75 mm) in females. The same dimensions were 34.85 mm, 3.91 mm, 10.26 mm, 12.81 mm, and 134.68 mm in males, respectively. There were statistically significantly differences in the frontal horn width, third (3rd) ventricle width, and the maximum transverse inner diameter of the skull values in between sexes. The mean values of Evans' index which obtanied with maximum width between the frontal horns of the lateral ventricles divided by the maximum transverse inner diameter of the skull were found as 0.280 ±0.172 in females; whereas the same dimensions were calculated 0.276±0.161 in males. These values were lower in healthy male subjects than females, however; there were no found significantly difference between groups. Present findings obtained from MRI are necessary anatomical baseline data for interpreting pathological changes, planning surgery, and determining presence and progress of some neurological diseases.


El objetivo de este estudio fue determinar los valores normales de los ventrículos e índices cerebrales en sujetos sanos en nuestra población mediante el uso de imágenes de resonancia magnética (RM) y revelar las diferencias relacionadas con el sexo y la edad. Se examinó la resonancia magnética de 265 individuos sanos de entre 18 y 87 años, y se utilizaron las imágenes en sentido medio y sagital para las mediciones. Las mediciones se realizaron a partir de IRM en una estación de trabajo. Se observaron los siguientes valores medios de ventrículos e índices cerebrales: longitud del asta frontal (FHW) (33,14 mm); longitud del tercer ventrículo (TVW) (3,37 mm); longitud anteroposterior del cuarto ventrículo (FVWAP) (9,93 mm); longitud transversal del cuarto ventrículo (FVWT) (12,40 mm); y el diámetro transversal máximo del cráneo (SID) (128,75 mm) en las hembras. Las mismas dimensiones fueron 34,85 mm, 3,91 mm, 10,26 mm, 12,81 mm y 134,68 mm en machos, respectivamente. Hubo diferencias estadísticamente significativas en el ancho del asta frontal, el ancho del tercer ventrículo y el diámetro interno transversal máximo de los valores del cráneo entre los sexos. Los valores medios del índice de Evans que obtuvieron el ancho máximo entre los cuernos frontales de los ventrículos laterales dividido por el diámetro interno transversal máximo del cráneo se encontraron en 0,280 ± 0,172 en las mujeres; mientras que las mismas dimensiones se calcularon en hombres (0,276 ± 0,161). Sin embargo, estos valores fueron más bajos en hombres sanos que en mujeres; no se encontraron diferencias significativas entre los grupos. Los hallazgos actuales obtenidos de IRM son datos anatómicos de referencia necesarios para interpretar los cambios patológicos, planificar la cirugía y determinar la presencia y el progreso de algunas enfermedades neurológicas.


Sujets)
Humains , Mâle , Femelle , Adolescent , Adulte , Adulte d'âge moyen , Sujet âgé , Sujet âgé de 80 ans ou plus , Jeune adulte , Imagerie par résonance magnétique , Ventricules cérébraux/anatomie et histologie , Ventricules cérébraux/imagerie diagnostique , Facteurs âges , Caractères sexuels
9.
Rev. argent. neurocir ; 33(1): 1-13, mar. 2019. ilus
Article Dans Espagnol | LILACS, BINACIS | ID: biblio-1177834

Résumé

Objetivos: A través del estudio cadavérico dividir al central core cerebral (CCC) en diferentes áreas y proponer para cada sector el abordaje neuroquirurgico correspondiente. Como objetivo secundario analizaremos la anatomía neuroquirúrgico cortical y subcortical del CCC. Introducción : El CCC es descripto como un bloque que descansa sobre el tronco del encéfalo. Incluye la ínsula, capsula extrema, claustro, capsula externa, núcleo lenticular, capsula interna, núcleo caudado y el tálamo. Material y Métodos: Se estudiaron 12 hemisferios cerebrales humanos adultos y una cabeza en el ­LaNeMic- de la Universidad de Buenos Aires, analizamos 9 casos de patologías neuroquirúrgicas del CCC y dibujos digitales de los abordajes propuestos para cada sector del CCC. Se tomaron fotografías de cada disección y las mediciones obtenidas con calibre digital. Resultados: Dividimos al CCC en un sector medial, intermedio y lateral; con subdivisiones específicas para el lateral y medial. La proyección lateral del foramen de Monro se encontró en el tercer giro corto de la ínsula con las distancias: MILA: 23,95 mm; MILP: 22,92 mm; SLS: 14,99 mm y SLI: 13,76 mm. Proponemos los siguientes abordajes: abordaje transcalloso homolateral, abordaje transcalloso contralateral, abordaje trans-fisura coroidea, abordaje trans-esplenial, acceso trans-parietal ingresando al surco intraparietal y abordaje trans-silviano. Discusión: Se deben analizar los estudios preoperatorios del paciente, comprendiendo las lesiones según la ubicación y de ese modo seleccionar el abordaje más preciso y seguro. Conclusiones: Se provee a través de este trabajo una descripción de los límites y anatomía del CCC, empleando disecciones cerebrales, análisis de casos operados y de medidas útiles para el neurocirujano.


Objectives: Through the cadaveric study, we divide the cerebral central core (CCC) in different areas and propose the corresponding neurosurgical approach for each sector. As a secondary objective, we will analyze the cortical and subcortical microsurgical anatomy of the CCC. Introduction: The CCC is described as a block that rests on the trunk of the brain. It includes the insula, extreme capsule, claustro, external capsule, lenticular nucleus, internal capsule, caudate nucleusand thalamus. Material and Methods: We studied 12 adult human brain hemispheres and one head in the -LaNeMic- of the University of Buenos Aires, analyzed 9 cases of CCC neurosurgical pathologies and digital drawings of the approaches proposed for each sector of the CCC. Photographs of each dissection and measurements obtained with digital caliber were taken. Results: We divide the CCC into a medial, intermediate and lateral sector; with specific subdivisions for the lateral and medial. The lateral projection of the foramen of Monro was found in the third short gyri of the insula with the distances: MILA: 23.95mm; MILP: 22.92mm; SLS: 14.99mm and SLI: 13.76mm. We propose the following approaches: ipsilateral transcallosal approach, contralateral transcallosal approach, choroidal trans-fissure approach, trans-splennial approach, trans-parietal access entering the intraparietal sulcus, and trans-silvian approach. Discussion: The preoperative studies of the patient should be analyzed, understanding the lesions according to the location and in this way selecting the most accurate and safe approach. Conclusions: A description of the limits and anatomy of the CCC is provided through this work, using brain dissections, analysis of operated cases and useful measurements for the neurosurgeon.


Sujets)
Tronc cérébral , Thalamus , Encéphale , Ventricules cérébraux , Anatomie , Neurochirurgie
10.
Journal of Central South University(Medical Sciences) ; (12): 1188-1195, 2019.
Article Dans Chinois | WPRIM | ID: wpr-813031

Résumé

Hydrocephalus is a common neurological disease with complex etiology. It is characterized by the accumulation and continuous growth of cerebrospinal fluid in the ventricular system and subarachnoid space. Hydrocephalus can be caused by congenital genetic factors, brain trauma and cerebral hemorrhage. Through the efforts of many researchers, the pathogenesis of hydrocephalus is being completed, but it has not been fully explained. The imbalance of cerebrospinal fluid production and absorption into the sinus, and disorder of the cerebrospinal fluid circulation pathway or the osmotic pressure maintenance in the ventricle can lead to increased cerebrospinal fluid and ventricular dilatation.


Sujets)
Humains , Hémorragie cérébrale , Ventricules cérébraux , Liquide cérébrospinal , Hydrocéphalie
11.
Pesqui. vet. bras ; 38(10): 1935-1941, out. 2018. tab, ilus
Article Dans Anglais | LILACS, VETINDEX | ID: biblio-976377

Résumé

This study aimed to determine age-related changes of the cerebral ventricles of healthy non-brachycephalic domestic cats by the acquisition of brain MRI images of 12 adult (1 to 6 years), 11 mature (7 to11 years) and 10 geriatric (12 years or more) cats. Our hypothesis is that the cerebral ventricular system of cats expands with increasing age. The possibility of the evidence of the olfactory bulb cavities and temporal horns of the lateral ventricles were evaluated in this study. Volumes of the olfactory bulb cavities, lateral ventricles (including the temporal horns), third ventricle, mesencephalic aqueduct and fourth ventricle were measured and corrected for the intracranial volume. Significant differences were found between the adult and mature groups in relation to the geriatric one for the variable related to the evidence of the temporal ventricular horns, which were most frequently visualized in geriatric cats. Percentage of the right lateral and third ventricles volume by intracranial volume were significantly higher in geriatric cats compared to the adults. The results of this study demonstrate that ventricular dilation tends to occur with advancing age in cats, as well as the increase in the frequency of the temporal ventricular horn evidence, as had been indicated in the hypothesis of the study.(AU)


O estudo objetivou a determinação das alterações senis dos ventrículos cerebrais de gatos domésticos hígidos não braquicefálicos pela aquisição de imagens encefálicas de 12 indivíduos adultos (1 a 6 anos), 11 maduros (7 a 11 anos) e 10 geriátricos (12 anos de idade ou mais) por ressonância magnética. Nossa hipótese é de que o sistema ventricular dos gatos se expande com o avanço da idade. A possibilidade de evidenciação das cavidades do bulbo olfatório e dos cornos temporais dos ventrículos laterais foi avaliada nesse estudo. Os volumes das cavidades do bulbo olfatório, ventrículos laterais (incluindo os cornos temporais), terceiro ventrículo, aqueduto mesencefálico e quarto ventrículo foram mensurados e corrigidos de acordo com o volume intracraniano. Diferenças significativas foram encontradas entre os grupos dos adultos e maduros em relação aos geriátricos para a variável referente à evidenciação dos cornos temporais, que foram visualizados de forma mais frequente nos gatos geriátricos. A porcentagem do volume do ventrículo lateral direito e do terceiro ventrículo em relação ao volume intracraniano foi significativamente maior nos animais geriátricos em comparação aos adultos. Os resultados desse estudo demonstram que a dilatação ventricular tende a ocorrer com o avanço da idade nos gatos, assim como o aumento na frequência da evidenciação dos cornos temporais, como havia sido indicado na hipótese do estudo.(AU)


Sujets)
Animaux , Chats , Vieillissement , Chats , Ventricules cérébraux/anatomie et histologie , Ventricules cérébraux/imagerie diagnostique , Imagerie par résonance magnétique/médecine vétérinaire
12.
Dement. neuropsychol ; 12(3): 321-325, July-Sept. 2018. graf
Article Dans Anglais | LILACS | ID: biblio-952975

Résumé

Abstract The debates about the mind and its higher functions, and attempts to locate them in the body, have represented a subject of interest of innumerable sages since ancient times. The doubt concerning the part of the body that housed these functions, the heart (cardiocentric doctrine) or the brain (cephalocentric doctrine), drove the search. The Egyptians, millennia ago, held a cardiocentric view. A very long time later, ancient Greek scholars took up the theme anew, but remained undecided between the heart and the brain, a controversy that lasted for centuries. The cephalocentric view prevailed, and a new inquiry ensued about the location of these functions within the brain, the ventricles or the nervous tissue, which also continued for centuries. The latter localization, although initially inaccurate, gained traction. However, it represented only a beginning, as further studies in the centuries that followed revealed more precise definitions and localizations of the higher mental functions.


Resumo Os debates sobre a mente e suas funções superiores, e as tentativas de estabelecer suas localizações no corpo, foram objeto de interesse de inúmeros sábios desde os tempos mais remotos. A dúvida quanto à parte do corpo que abrigava tais funções, o coração (doutrina cardiocêntrica) ou o cérebro (doutrina cefalocêntrica), abriu as buscas. Os egípcios, há milênios, mantinham um ponto de vista cardiocêntrico. Muito tempo depois, antigos acadêmicos gregos retomaram o tema, mas permaneceram indecisos entre o coração e o cérebro, uma controvérsia que durou séculos. O ponto de vista cefalocêntrico predominou, e seguiu-se uma nova questão, quanto ao lugar dessas funções no cérebro, os ventrículos ou o tecido nervoso, que também durou séculos. Esta última localização, apesar de inicialmente equivocada, prosperou. Entretanto, esta representou apenas um começo, já que mais estudos, nos séculos seguintes, revelaram definições e localizações mais precisas para as funções mentais superiores.


Sujets)
Activité nerveuse supérieure , Ventricules cérébraux , Histoire de la médecine , Tissu nerveux
13.
Rev. bras. neurol ; 53(3): 41-46, jul.-set. 2017. tab, graf
Article Dans Anglais | LILACS | ID: biblio-876877

Résumé

Introduction: Normal aging is associated with morphological alte-rations in brain. Ventricular system is located deep inside brain and reflect the overall process of parenchymal atrophy. Once neurode-generative disorders course with more prominent dilatation of brain ventricles, to establish normative volumetric parameters from Brazi-lian healthy old individuals is necessary, and it may be an additional tool on differentiation from the normal to pathological. Objective: To investigate brain ventricular volume changes in Brazilian healthy el-derly people. Methods: Transversal study using magnetic resonance imaging (1.5T) of the brain from 21 elderly healthy volunteers (67±6 years old). Data were assessed with manual segmentation techni-que. Regions of interest were the brain ventricles and intracranial volumes. Old (60-69 years old, 15 women) and Older (>69 years old) groups were created for analysis. Results: Volume of all ventricular compartments significantly increased (p<.001) with age, with excep-tion of the fourth ventricle. The third and lateral ventricles increased between groups 2.1- and 2.8-fold, respectively. Mean total ventricular volume was 1.2±.4% of intracranial volume in Old and 3.2±1.8% in Ol-der group (p<.001), which represents 15±6ml and 40±24ml (p=.001), respectively. We observed a moderate to strong positive correlation between ventricular volume and age, with the best correlation in the third ventricle (r=.710). Total intracranial volume diminished with age, but without statistical significance. Conclusions: Brain ventricles vo-lume increased significantly with age in healthy old individuals, with exception of the fourth ventricle. (AU)


Introdução: O envelhecimento normal está associado a alterações morfológicas do cérebro. O sistema ventricular está localizado pro-fundamente no encéfalo e reflete o processo global de atrofia do pa-rênquima. Uma vez que doenças neurodegenerativas cursam com dilatação mais proeminente dos ventrículos cerebrais, estabelecer parâmetros volumétricos de normalidade em nossa população idosa saudável se faz necessário, podendo ser uma ferramenta a mais para diferenciar o normal do patológico. Objetivo: Investigar alterações volumétricas dos ventrículos cerebrais em brasileiros idosos sau-dáveis. Métodos: Estudo transversal com imagens de ressonância magnética (1,5T) do encéfalo de 21 idosos saudáveis (68±6 anos, 15 mulheres). Os dados foram examinados por técnicas de segmenta-ção manual. As regiões de interesse foram os ventrículos cerebrais e o volume intracraniano. Criamos os subgrupos Idosos (60-69 anos) e Mais idosos (>69 anos) para a análise. Resultados: O volume de todos os ventrículos aumentou com a idade (p<0,001), com exceção do quarto ventrículo. O terceiro e os ventrículos laterais aumentaram 2,1 e 2,8 vezes, respectivamente, entre os grupos. O volume ventri-cular médio foi de 1,2±0,4% do volume intracraniano nos Idosos e de 3,2±1,8% nos mais idosos, o que representa 15±6ml e 40±24ml, respectivamente. Observamos correlação positiva de moderada a forte entre volume ventricular e idade, com a melhor correlação no terceiro ventrículo (r=0,710). O volume intracraniano diminui com a idade, sem significância estatística. Conclusão: os ventrículos cere-brais aumentam significativamente com o envelhecimento em idosos saudáveis, exceto o quarto ventrículo. (AU)


Sujets)
Humains , Mâle , Femelle , Sujet âgé , Encéphale/physiologie , Vieillissement , Ventricules cérébraux/imagerie diagnostique , Atrophie/imagerie diagnostique , Imagerie par résonance magnétique/méthodes , Modèles linéaires , Études transversales , Reproductibilité des résultats
14.
Rev. chil. neurocir ; 43(1): 74-82, July 2017. ilus
Article Dans Anglais | LILACS | ID: biblio-869782

Résumé

Introducción: A hemisferectomía es un procedimiento valioso en el tratamiento de trastornos convulsivos causados por desordenes hemisféricos unilaterales. El hemisferectomía anatómica se ha utilizado para este fin desde 1938, sin embargo, se abandonó este procedimiento después de informes de complicaciones postoperatorias causadas por hemosiderosis superficial, ependimitis e hidrocefalia obstructiva. Así que, se ha mostrado en la literatura modificaciones en las indicaciones y técnicas de hemisferectomía anatómica cuya finalidad es la de reducir la incidencia de esta complicación sin dejar de lograr control de las convulsiones. Sobre la base de la literatura, la hemisferectomía mejora la calidad de vida de los pacientes que tiene la indicación para realizar este procedimiento, ya que permite reducir la frecuencia de las convulsiones, si tónica o átona, tónico-clónicas Objetivo: El objetivo de esta revisión de la literatura es discutir los detalles técnicos, modalidades, riesgos, complicaciones, resultados y de pronóstico de hemisferectomía basado en la revisión crítica de la literatura. Casuística y Métodos: Se realizó la consulta bibliográfica, utilizando la base de datos MEDLINE, LILACS, SciELO, que utiliza el lenguaje como criterios de selección, la elección de los artículos recientes preferiblemente en portugués, español o inglés. Conclusión: Según las referencias, hemisferectomía es un procedimiento con buen resultado para las personas con convulsiones derivadas cuando está indicado para casos seleccionados y la tasa de éxito no es proporcional a la extensión de la resección del tejido neuronal. A mayor resección puede o no reducir la frecuencia de las crisis, sin embargo, la incidencia de la morbilidad puede ser mayor.


Background: The hemispherectomy is a valuable procedure in the management of seizure disorders caused by unilateral hemispheric disease. The anatomical hemispherectomy has been used for this purpose since 1938, however, it was abandoned after reports of postoperative complications caused by superficial hemosiderosis, ependymitis and obstructive hydrocephalus. So that, it has been showed modifications in the techniques of hemispherectomy whose the purpose is reduce the incidence of this complications while still achieving seizure control. Based on literature, the hemispherectomy improves the quality of life of patients that has the indication to perform this procedure because it allows reducing the frequency of seizures, whether tonic or atonic, tonic-clonic. Aim: The aim of this literature review is discuss the indications, technical details, modalities, risks, complications, results as well de prognosis of callosotomy based on critical literature review and the authors experience. Casuistry and Methods: It was performed bibliographical consultation, using the databases MEDLINE, LILACS, SciELO, utilizing language as selection criteria, choosing preferably recent articles in Portuguese, Spanish or English. Conclusion: According to references, the functional hemispherectomy has a good outocome for those with seizures arisin when indicated to selected cases and the success rate is not proportional to the extent of neuronal tissue resection. So that, a greater resection cannot necessarily reduce the seizure frequency, however the morbidity may also be larger.


Sujets)
Humains , Cerveau/chirurgie , Cerveau/physiopathologie , Crises épileptiques/chirurgie , Épilepsie/chirurgie , Hémisphérectomie/effets indésirables , Hémisphérectomie/méthodes , Hémisphérectomie/mortalité , Ventricules cérébraux/chirurgie , Nerfs crâniens , Hémosidérose , Pronostic
15.
Journal of Korean Neurosurgical Society ; : 604-609, 2017.
Article Dans Anglais | WPRIM | ID: wpr-200247

Résumé

OBJECTIVE: An adjustable Ghajar guide is presented to improve the accuracy of the original Ghajar guide technique. The accuracy of the adjustable Ghajar guide technique is also investigated. METHODS: The coronal adjustment angle from the orthogonal catheter trajectory at Kocher's point is determined based on coronal head images using an electronic picture archiving and communication system. For the adjustable Ghajar guide, a protractor is mounted on a C-shaped basal plate that is placed in contact with the margin of a burrhole, keeping the central 0° line of the protractor orthogonal to the calvarial surface. A catheter guide, which is moved along the protractor and fixed at the pre-determined adjustment angle, is then used to guide the ventricular catheter into the frontal horn adjacent to the foramen of Monro. The adjustable Ghajar guide technique was applied to 20 patients, while a freehand technique based on the surface anatomy of the head was applied to another 47 patients. The accuracy of the ventricular catheter placement was then evaluated using postoperative computed tomography scans. RESULTS: For the adjustable Ghajar guide technique (AGT) patients, the bicaudate index ranged from 0.23 to 0.33 (mean±standard deviation [SD]: 0.27±0.03) and the adjustment angle ranged from 0° to 10° (mean±SD: 5.2°±3.2°). All the AGT patients experienced successful cerebrospinal fluid diversion with only one pass of the catheter. Optimal placement of the ventricular catheter in the ipsilateral frontal horn approximating the foramen of Monro (grade 1) was achieved in 19 patients (95.0%), while a suboptimal trajectory into a lateral corner of the frontal horn passing along a lateral wall of the frontal horn (grade 3) occurred in 1 patient (5.0%). Thus, the AGT patients experienced a significantly higher incidence of optimal catheter placement than the freehand catheterized patients (95.0% vs. 68.3%, p=0.024). Moreover, none of the AGT patients experienced any tract hemorrhages along the catheter or procedure-related complications. CONCLUSION: The proposed adjustable Ghajar guide technique, using angular adjustment in the coronal plane from the orthogonal trajectory at Kocher’s point, facilitates accurate freehand placement of a ventricular catheter for hydrocephalic patients.


Sujets)
Animaux , Humains , Cathétérisme , Cathéters , Ventricules cérébraux , Liquide cérébrospinal , Tête , Hémorragie , Cornes , Hydrocéphalie , Incidence , Projets pilotes , Dérivation ventriculopéritonéale
16.
Brain Tumor Research and Treatment ; : 37-41, 2017.
Article Dans Anglais | WPRIM | ID: wpr-63841

Résumé

We report a rare case of subependymal giant cell astrocytoma (SEGA) associated with tumoral bleeding in a pediatric patient without tuberous sclerosis complex (TSC). A 10-year-old girl presented with a 2-week history of an increasingly aggravating headache. Brain magnetic resonance imaging revealed an approximately 3.6-cm, well-defined, heterogeneously enhancing mass with multistage hemorrhages on the right-sided foramen of Monro. The tumor was completely resected using a transcallosal approach. Intraoperatively, the mass presented as a gray-colored firm tumor associated with acute and subacute hemorrhages. The origin of the mass was identified as the ventricular septum adjacent to the foramen of Monro. A pathological analysis revealed pleomorphic multinucleated eosinophilic tumor cells with abundant cytoplasm. These cells showed positive staining for the glial fibrillary acidic protein and S100 protein. A diagnosis of SEGA was established. The patient recovered without any neurological symptoms. There was no evidence of TSC. The radiological follow-up showed no recurrence for 2 years. This was a case of SEGA with intratumoral hemorrhage, for which a favorable outcome was achieved, without any neurological deficit after tumoral resection.


Sujets)
Enfant , Femelle , Humains , Astrocytome , Encéphale , Ventricules cérébraux , Cytoplasme , Diagnostic , Granulocytes éosinophiles , Études de suivi , Protéine gliofibrillaire acide , Céphalée , Hémorragie , Imagerie par résonance magnétique , Récidive , Complexe de la sclérose tubéreuse , Septum interventriculaire
17.
Rev. chil. neurocir ; 42(2): 102-106, nov. 2016. ilus, tab
Article Dans Espagnol | LILACS | ID: biblio-869759

Résumé

El siguiente trabajo constituye una nota técnica sobre un nuevo proceder endoscópico de colocación de catéteres ventriculares permanente a través del cuerno occipital. Se colocaron 20 catéteres permanentes utilizando el sistema DECK con un endoscopio Hopkins II de 30°, diámetro 2,7 mm y longitud 30 cm, con vainas y canales de trabajos. La posición del catéter fue evaluada por tomografía de cráneo realizada a las 24 horas de la cirugía, obteniéndose una posición a (óptima) en el 95 por ciento de los casos, con una distancia promedio de 10,5 cm desde la tabla externa del hueso occipital al cuerno frontal. En ninguno de los casos disfuncionó el sistema derivativo y un solo paciente presentó como complicación un hematoma del lecho quirúrgico.


The following papers is a technical note about a new endoscopic access to lateral ventricle through occipital horn to place ventricles catheters, 20 patient was operated using Deck System of endoscopy with lens of 30 grades, 2,7 mm of diameter and 30 cm of larger, sheets and working canals including. CT scan was performing 24 hours after surgery and optimal position was obtained in 95 percent. Median distance from occipital bon to frontal horn of the ventricles was 10,5 cm. Any patient present dysfunction of the system and only one patient had a hematoma of the surgical area.


Sujets)
Humains , Adulte d'âge moyen , Cathéters , Dérivation ventriculopéritonéale/méthodes , Endoscopie/méthodes , Os occipital , Ventricules cérébraux/chirurgie , Ventriculographie cérébrale , Plexus choroïde , Hématome
18.
Rev. chil. neurocir ; 42(2): 156-159, nov. 2016. ilus
Article Dans Espagnol | LILACS | ID: biblio-869769

Résumé

El Sistema Ventricular Cerebral se desarrolla de forma paralela al resto del Sistema Nervioso Central, facilitando la circulación del Líquido Cefalorraquídeo, desde su separación del líquido amniótico a nivel embrionario. Este desarrollo es necesario para entender correctamente la anatomía ventricular y facilitar el abordaje para patologías intraventriculares. El objetivo de esta revisión es reconocer los puntos más importantes en la embriología ventricular para facilitar el aprendizaje de la anatomía quirúrgica ventricular.


The cerebral ventricular system is developed in parallel with the rest of the central nervous system, facilitating the circulation of cerebrospinal fluid, from the amniotic fluid separation in the embryonic phases. This development is necessary to correctly understand the ventricular anatomy and facilitate approach to intraventricular pathologies. The objective of this review is to recognize the most important points in the ventricular embryology and in the intraventricular endoscopic vision to facilitate learning of the ventricular surgical anatomy.


Sujets)
Humains , Endoscopie/méthodes , Ventricules cérébraux/embryologie , Ventriculostomie/méthodes , Système nerveux central , Tube neural
19.
JCPSP-Journal of the College of Physicians and Surgeons Pakistan. 2016; 26 (1): 77-77
Dans Anglais | IMEMR | ID: emr-175812
20.
Acta cir. bras ; 30(12): 819-823, Dec. 2015. tab, graf
Article Dans Anglais | LILACS | ID: lil-769506

Résumé

ABSTRACT PURPOSE: To develop an experimental model of neurocysticercosis-induced hydrocephalus METHODS: There were used 17 rats. Ten animals were inoculated with Taenia crassiceps cysts into the subarachnoid. Five animals were injected with 0.1ml of 25% kaolin (a standard solution for the development of experimental hydrocephalus) and two animals were injected with saline. Magnetic resonance imaging (MRI) was used to evaluate enlargement of the ventricles after one or three months of inoculation. Volumetric study was used to quantify the ventricle enlargement. RESULTS: Seven of the 10 animals in the cyst group developed hydrocephalus, two of them within one month and five within three months after inoculation. Three of the five animals in the kaolin group had hydrocephalus and none in the saline group. Ventricle volumes were significantly higher in the 3-months MRI cyst subgroup than in the 1-month cyst subgroup. Differences between cyst subgroups and kaolin group did not reach statistical significance. CONCLUSION: The developed model may reproduce the human condition of neurocysticercosis-related hydrocephalus, which exhibits a slowly progressive chronic course.


Sujets)
Animaux , Modèles animaux de maladie humaine , Hydrocéphalie/induit chimiquement , Neurocysticercose/parasitologie , Ventricules cérébraux/effets des médicaments et des substances chimiques , Ventricules cérébraux/anatomopathologie , Kaolin , Imagerie par résonance magnétique , Neurocysticercose/anatomopathologie , Projets pilotes , Rat Wistar , Taenia
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