Résumé
La confirmación de un caso probable o sospechoso de infección por MERS-CoV (según criterios clínicos y epidemiológicos), sólo puede ser realizada mediante pruebas de laboratorio. Sin embargo, otros patógenos respiratorios virales (incluyendo, pero no limitado a: Influenza, Virus Sincitial Respiratorio, otros beta y alphacoronavirus humanos comunes) y bacterianos (Streptococcus pneumoniae, Haemophilus influenzae tipo b, Legionella pneumophila) deben ser considerados dentro del algoritmo diagnóstico.
Sujets)
Virologie/instrumentation , Infections à coronavirus/prévention et contrôle , Pandémies/prévention et contrôle , Coronavirus du syndrome respiratoire du Moyen-Orient/génétique , Coronavirus du syndrome respiratoire du Moyen-Orient/pathogénicitéRésumé
The aim of the present study was to estimate hepatitis B virus seroprevalence among first-time blood donors in the city of Campo Grande, Mato Grosso do Sul State, in the central-western region of Brazil. Findings A retrospective analysis of first-time voluntary blood donor records, from January 2010 to December 2010, was conducted at the Hematology Center of Mato Grosso do Sul. The prevalence of the HBsAg and anti-HBc serological markers and their respective 95% confidence intervals were calculated. Chi-square analysis was performed between the seroprevalence previously found in 2001 and the one determined by the current study. Results were considered statistically significant if p< 0.05. Among 8,840 subjects, 269 (3.04%, 95% CI: 2.7-3.4) were positive for HBV markers. The prevalence rate of HBsAg was 0.19% (95% CI: 0.1-0.3) and anti-HBc alone was 2.85% (95% CI: 2.5-3.2). Conclusions There was no statistically significant difference regarding gender. However, an important association was observed between HBV infection and older age (p< 0.01). The seroprevalence of HBV infection in first-time blood donors diminished from 2001 to 2010 (p< 0.01). Such decrease suggests an improvement in the recruitment of safe donors, the positive impact of vaccination programs and the decreasing of HBV infection prevalence in the general population.