Awareness, treatment and control of hypertension, dyslipidaemia and diabetes mellitus in an Iranian population: the IHHP study

We used data from the baseline survey from the Isfahan Healthy Heart Programme to determine the prevalence of hypertension, dyslipidaemia and diabetes among a representative samples of 12 514 adults living in 3 cities in the Islamic Republic of Iran. The prevalence of hypertension, dyslipidaemia and diabetes was 17.3%, 66.3% and 5.6% respectively. Awareness, treatment and control of hypertension were 40.3%, 35.3%, and 9.1% respectively. The rates for dyslipidaemia were 14.4%, 7.1% and 6.5% respectively, and 54.6% of diabetics were aware of their disease and 46.2% were under treatment

Cardiovascular disease risk factors, metabolic syndrome and obesity in an Iranian population

As part of the Isfahan Healthy Heart Program, we evaluated the prevalence of cardiovascular disease risk factors in Iranians with generalized and abdominal obesity. We carried out a crosssectional study on 3694 participants aged >/= 19 years. Overall, 36.6% of men and 35.9% of women were overweight; 11.2% of men and 28.1% of women were obese. Mean body mass index [BMI], waist circumference [WC] and waist/hip ratio [WHR] increased with age up to 65 years. Total serum cholesterol, triglycerides and 2-hour post-load plasma glucose increased with BMI, WC and WHR in both sexes. Prevalence of metabolic syndrome was 19.8% in females with normal BMI, 48.1% in overweight females and 63.2% in obese females. In males, corresponding values were 3.7%, 18.0% and 40.1%

Immunogenicity of recombinant hepatitis B vaccine in Iranian neonates: high frequency of unresponsiveness independeut of the carrier state of mothers

Immunogenicity of a recombinant hepatitis B vaccine was evaluated in a number of Iranian neonates. Of 1176 neonates vaccinated with triple doses of the vaccine at 0, 1 and 6 months, 7.4% failed to respond and did not develop a protective titer of anti-HBs antibody [>/= 10 IU/1]. Titration of anti-HBs antibody allowed classification of both responder and non-responder vaccinees into negative or borderline non-responders and low, intermediate or high responders, respectively. Unresponsiveness to the vaccine was similarly represented in both male and female vaccinees. HBs antigen was negative in all responder and non-responder neonates tested and their mothers, suggesting lack of correlation between unresponsiveness of the neonates to recombinant HBs antigen and the carrier status of the mothers