Epidemiological and pathological features of cancer in Fez Boulemane region, [Morocco]

In Fez-Boulemane, Morocco, there is no cancer registry so there is a lack of information about the incidence and characteristics of cancer in the region. In this retrospective study we examined the epidemiological and pathological features of 5532 cases of cancer collected from the Department of Pathology in Hassan II University Hospital of Fez from 2004 to 2010. The mean age of the patients was 53.5 years and 52% were male. Digestive cancers and skin cancers were the most common. Digestive cancers were predominantly colorectal and stomach. Cancers of the urinary bladder and colorectal cancers were the leading cancers in men accounting respectively for 9% and 8% of all male cancers. In women, cancers of the breast [62%] and uterine cervix [22.6%] predominated. As a first step in cancer control in our area, establishment of a regional cancer registry is recommended

Post-menopausal endometrial tuberculosis mimicking carcinoma: an important differential diagnosis to consider

We report the case of a menopausal 74-year-old patient who presents pyorrhoea for 6 months. We suspect initially a carcinoma process, but the anatomopathological examination takings obtained by biopsy curettage of the endometrial under hysteroscopy is in favor of an inflammatory infiltrate with epithelioid and giant cells of type Langhans and type Muller without caseous necrosis. The bacteriological direct examination after coloring of Gram, Ziehl-Neelsen and Sabouraud was negative. The bacteriological culture in the L"ewenstein and Coletsos environment identified Mycobacterium tuberculosis. The searches for another source of the infection was negative both at the pulmonary and urinary levels. An antituberculous quadritherapy allows the fast clinical improvement. The tuberculosis remains frequent but rarely genital. It is especially the case of young women, from non industrialized countries, consulting for infertility. It is necessary to know how to evoke it front in pelvic symptoms, whatever the age is and to realize easily mycobacteriological examinations

[Role of cervical smear in the diagnosis of cervical cancer in Fes-Boulemane region of Morocco]

A retrospective study was conducted between 2000 and 2003 on 1620 women [mean age 39.6 years] in northern Morocco to determine the incidence of cervical cancer and assess the value of cervical smear in the diagnosis. Patients were interviewed using a questionnaire before carrying out a gynaecological examination and taking a cervical smear sample. Of the total sample, 23.1% had an abnormal cervical smear, of whom 5.6% showed intraepithelial lesions, both low and high grade. The women presenting with cervicitis represented the highest percentage with suspect smears [30.8%]; 90.9% of the smears showing high grade lesions were histologically confirmed as cervical cancer. A screening programme is a matter of urgency in northern Morocco

Solitary infantile myofibromatosis of the orbit

Infantile myofibromatosis [IM] is an extremely rare cause of skull lesion in the new-born and paediatric population. The prognosis is related to the number of lesions and the presence or absence of visceral involvement. The authors report a case of IM, in a 5-year-old boy with an osteolytic lesion in the right orbital roof, which displaced the globe downwards. A subfrontal approach was made with total resection. The globe had regained a normal position and further evaluation revealed no other lesions. The patient's age at presentation, physical findings, radiographic appearance and the histopathological examination of the lesion are needed to generate a-differential diagnosis and to formulate a treatment plan

astrocytomes sous ependymaires a cellues geantes au cours de la sclerose tubereuse de Bourneville.Etude histologique et immunohistochimique de 2 cas

In this study, we report 2 cases of subependymal giant cell astrocytomas associated with a Bourneville tuberous sclerosis in 2 children These 2 cases are studied using morphological and immunohistochemical methods which contributes to the study of these particular tumors