RESUMO
Troponin is frequently requested in the emergency department thanks to its use in the diagnosis and management of acute coronary syndrome. However, its demand often goes beyond the scope of international recommendations. A cross sectional study was carried out on a cohort of patients consulting at Cheikh Zaid hospital from July 9, 2018 to August 17, 2018. The trial was performed according to the "ARCHITECT STAT High sensitive troponin-I" method. Out of the 71 patients studied for troponin, 19 returned positive [26% of them]. Among the positive patients, 8 had acute coronary syndromes [42%] and 4 other heart problems. The average age was 63, with minimal and maximal of 48 and 84 respectively. Males were over-represented over females with a ratio of 63%. 63% of the positive patients had several additional cardiovascular risk factors. 26% of them had a normal ECG. Troponin is overused considering the small percentage of patients with acute coronary syndromes
RESUMO
Introduction: is to determine the prevalence of the hemolysed samples and to study the interference of hemoloysis on the determination of 17 current biochemical parameters: 3 electrolytes [K[+], Ca[2][+], PO[4] [2]]; 8 substrates [cholesterol, triglycerides, total bilirubin, direct bilirubin, glucose, uric acid, rate of protids, creatinin], 6 enzymes [LDH, ASAT, GGT, CK, ALAT, ALP]
Material and method: The study, concerning 34 patients performed blood samples for each patient on dry tubes without freezing, on one of these 2 samples we carried out a hemolysis by agitation [mechanical manner], after centrifugation of the two tubes we made the biochemical parameters assay. The study of the prevalence of the hemolysis samples was carried out by counting the number of hemolysed samples among the whole of samples received at the laboratory during six weeks
Results: Potassium; cholesterol, tiglycerides, total bilirubin, direct bilirubin; uric acid, LDH, ASAT; ALAT, CK and ALP were positively influenced by hemolysis, whereas the influence was negative for glucose, and creatinin. calcium, phoshorus, rate of protids, and GGT did not show significant variations. The prevalence of the hemolysed samples in the clinical biochemistry laboratory was 4,8%
Conclusion: The most common biochemical parameters are influenced by hemolysis, which conducts us to insist on control of the pre-analytical phase of sampling