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Journal of Arak University of Medical Sciences-Rahavard Danesh. 2009; 11 (4): 1-7
em Persa | IMEMR | ID: emr-101250

RESUMO

Imbalance between the production of free radicals and the antioxidant defense system causes oxidative stress. The cardamom is the fruit of the Elettaria cardamomum maton which probably has an antioxidant property. Aim of this study is assess of effect of cardamom-tea watery extract on oxidative stress. This clinical trial research was carried out on 54 persons. Firstly 5ml venous blood was collected and the parameter of the oxidative stress in their blood was evaluated. Then they were given every day 3 grams of cardamom and 1 gram of tea as like as 100 ml cardamom-tea watery extract for two weeks. After 2 weeks 5 ml blood was collected and the parameters of oxidative stress in their blood serum was evaluated for the second time. The parameters of first and second group of bloods were compared by SPSS software. The mean of total antioxidant capacity of serum before and after cardamom-tea extract were 1.96 +/- 0.64 micro mol/ml and 2.23 +/- 0.46 micro mol/ml respectively [p=0.009]. The mean of lipid peroxidation before and after cardamom-tea were 14.97 +/- 3.58 nmol/ml and 12.07=/-5.91 nmol/ml respectively [p=0/002]. The mean of total thiol group before and after cardamom-tea were 0.244 +/- 0.200, 0.266 +/- 0.166nmol respectively [p=0.141]. Th cardamom- tea reduces the amount of lipid peroxidation and enhanced the antiosidant markedly. So, the cardamom-tea decreases the amount of oxidative stress in blood. Therefore the cardamom-tea in the people diet is useful


Assuntos
Humanos , Estresse Oxidativo , Peroxidação de Lipídeos , Radicais Livres/efeitos adversos , Antioxidantes , Extratos Vegetais , Plantas Medicinais , Sequestradores de Radicais Livres
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