Effect of aqueous and alcoholic extracts of roots of Ferula gummosa Boiss. on the growth of Pseudomonas aeruginosa

Ferula gummosa Boiss. [Barije.] contain medical and antimicrobial properties. This study was done to determine the effect of aqueous and alcoholic extracts of roots of Ferula gummosa Boiss. on the growth of Pseudomonas aeruginosa. In this laboratory study, the plant was dried in dark place and aqueous, alcoholic extracts of Barije's root, powder were prepared using Soxhlet method. The efficacy of 0.1 dilution of different values of extracts of Ferula gummosa Boiss. on the strain of Pseudomonas aeruginosa [PTCC 1430] were evaluated by disk diffusion, Agar-well diffusion, minimum inhibitory concentration [MIC] and minimum bactericidal concentration [MBC] methods. Pseudomonas aeruginosa was completely resistant to the aqueous extract, and the MIC for the methanol and ethanol extracts was 1.25x10[4] microg/ml and 6.25x10[3] microg/ml, respectively. Methanolic and ethanolic extracts of Ferula gummosa Boiss. have antimicrobial activity against Pseudomonas aeruginosa in in-vitro model

[Evaluation short and long term graft and survival rates in kidney transplanted patients between 1995-2011]

Renal transplantation is a treatment of choice in most of the patients with end-stage of renal disease. Graft and patients survival rates are important issues for these patients and results are different in many centers throughout the world. Renal transplantation has been done in more than 25 centers till now in Iran. In this study, the short-term and the long-term graft survival rates of patients undergoing kidney transplants from living or deceased donor was evaluated in a cohort study and compared with other kidney transplants centers. In this cohort study, 353 consecutive patients [age from 11 to 65 years] with end stage renal disease [ESRD] between March 1995 and March 2011 attending to Shohada-Tajrish Hospital, Tehran, Iran, were recruited. SPSS software version 16 and Kaplan-Meier method were used to determine the survival rate. The one-month graft and patients survival rates were 93.2% and 99%, the one-year graft respectively. The patients survival rates were 89% and 97.4% and five-year graft and patients survival rates were 82.5 and 89.1% respectively. The serum creatinine level one month after transplantation [P=0.016], the age [P=0.12] and sex [P=0.012] of donor were showed to be the most important factors affecting the graft survival rate. Totally, according to the obtained results in this study, it could be conclude that the patients under evaluation in this study had a satisfactory short and long term graft survival rate compared with other large centers in the world. The most important factors for good graft survival were creatinine level at discharge, age and sex of donor