Comparative study on the effectiveness of coumavec and zinc phosphide in controlling zoonotic cutaneous leishmaniasis in a hyperendemic focus in central Iran

Zoonotic cutaneous leishmaniasis [ZCL] is an increasing health problems in many rural areas of Iran. The aim of this study was to introduce a new alternative rodenticide to control the reservoirs of ZCL, its effect on the vector density and the incidence of the disease in hyperendemic focus of Esfahan County, central Iran. The study was carried out from January 2011 to January 2012. In intervention areas, rodent control operation was conducted using zinc phosphide or Coumavec. Active case findings were done by house-to-house visits once every season during 2011-2012. To evaluate the effect of rodent control operation on the vector density, sand flies were collected twice a month using sticky traps. The reduction rate of rodent holes in intervention areas with Coumavec and zinc phosphide were 48.46% and 58.15% respectively, whereas in control area results showed 6.66 folds intensification. The Incidence of ZCL significantly reduced in the treated areas. Totally, 3200 adult sand flies were collected and identified in the intervention and control areas. In the treated area with zinc phosphide, the density of Phlebotomus papatasi was higher in outdoors in contrast with the treated area by Coumavec which the density of the sand fly was higher in indoors. Both rodenticides were effective on the incidence of ZCL and the population of the reservoirs as well. Coumavec seems to be effective on the outdoor density of the vector. This combination of rodenticide-insecticide could be a suitable alternative for zinc phosphide while bait shyness or behavioral resistance is occurred

Epidemiology of breast cancer in the Islamic Republic of Iran: first results from a population-based cancer registry

This study presents the first population-based report on breast cancer in the Islamic Republic of Iran using data derived from a cancer registry. A retrospective study was conducted to find all new breast cancer cases in 5 provinces covered by the cancer registry during the 5-year period 1996-2000. There were 2421 cases recorded in the 5 registries. The age-standardized incidence rate [ASR] was 16.2 per 100 000 person-years. In contrast to more developed countries, the ASR of breast cancer was low, with the lowest rate seen in Ardabil province

first population-based Cancer survey in Kerman province of Iran

Cancer is the second most common cause of non-accidental death in Iran. Geographical, racial and habitual differences have led to the variation in the incidence of cancer in different regions of this country. This study was performed to determine the incidence of cancer in the Kerman Province, central Iran. All newly diagnosed cases of cancer in the Kerman Province were recorded in a five-year period [1996-2000]. In all, 5884 new cases [55.7% males] of cancer were found after elimination of repeated cases. Based on age-standardized incidence rates [ASR] the most common cancers in men were stomach [10.2], lung [7.1], bladder [6.7], colorectal [5.9] and non-Hodgkin's lymphoma [5.8], while in women the most common cancers were breast [16.9] colorectal [5.9], stomach [5.1], leukaemia [4.6] and non-Hodgkin's lymphoma [2.8]. For all cancers, ASR was 76 for males and 68 for females. The results indicate that upper gastrointestinal cancer, especially oesophageal cancer is very rare in central Iran in contrast to northern Iran, although these types of cancers are some of the most common cancers in the Kerman Province