RESUMO
A 17 year old Sudanese female with breast lump and ovarian mass proved to be Burkitt's lymphoma of the breast and ovary. She received 8 cycles of CHOP chemotherapy and Intrathecal methotrexate and achieved complete response. Three years after treatment she is well without recurrence. A lymphoma should always be considered in the differential diagnosis of a breast tumor, especially in very young patients. It needs a different work-up and treatment
Assuntos
Humanos , Feminino , Neoplasias da Mama , Neoplasias Ovarianas , Linfoma de Burkitt/tratamento farmacológico , Ciclofosfamida , Doxorrubicina , Vincristina , Prednisona , MetotrexatoRESUMO
A prospective study was carried out in an area of unstable malaria transmission in central Sudan to determine the efficacy and toxicity of quinine in pregnancy. Thirty-three pregnant women with severe Plasmodium falciparum malaria at mean 28.8 weeks gestational age were treated with quinine for 7 days. The mean body temperature on presentation for 3 patients who delivered prematurely was significantly higher than for those who delivered at term [39.2 +/- 0.7 degrees C versus 38.7 +/- 1.3 degrees C]. There were no significant difference between the 2 groups in other clinical or biochemical parameters. There were no clinically detectable congenital malformations and no auditory, visual or other neurological deficits in the babies at birth or 6 months later. Quinine may be safe in the treatment of severe falciparum malaria during pregnancy