Detection of an early marker of atherosclerosis among non-insulin dependent-diabetic patients

An early marker of subclinical arteriosclerosis, the increased intimal-medial thickness [IMT] of the common carotid artery was measured by B-mode ultrasound in twenty non-diabetic and thirty non- insulin- dependent diabetic patients [ten newly diagnosed and twenty well established diabetics]. This marker was compared in non- diabetic and diabetic subjects to evaluate its correlation with some cardiovascular risk factors, and duration of diabetes. In addition, body mass index [BMI], waist to hip ratio [WHR], blood pressure, glycosylated hemoglobin [HbAic] and fasting concentrations of plasma glucose, serum lipids and serum insulin were measured in all subjects. In conclusion, diabetes is characterized by a greater thickness of the carotid artery, which lead to increased risk of arteriosclerosis. Also, central adiposity is considered as a predictor of IMT in non- diabetic individuals

Histopathological and morphometric study of liver cell dysplasia in comparison with other chronic hepatic lesions

27 cases of cirrhosis with liver cell dysplasia [LCD] were evaluated and the results were compared with 11 cases of cirrhosis without LCD, 12 cases of chronic hepatitis, 15 cases of hepatocellular carcinoma and 5 cases of normal control. The morphometric study showed that the nuclear-cytoplasmic, nucleolar cytoplasmic and nucleolar-nuclear ratios were significantly higher in LCD than that observed in non neoplastic group while, the nuclear-cytoplasmic and nucleolar cytoplasmic ratios of hepaocellular carcinoma were significantly higher than those in LCD but the latter had nucleolar-nuclear ratio similar to that of neoplastic cells. These results suggested the pre- malignant nature of LCD and of important clinical appliction in regular follow up of the patients with LCD

Evaluation of antileprotic drugs in the treatment of rhinoscleroma

This study has been conducted on 30 patients suffering from rhinoscleroma. All patients have been given antileprotic drugs [dapson 100 mg every day and lamprene 100 mg every other day] for 3 months to estimate the effect of these drugs on this resistant disease. Histopathological examination of biopsy specimens taken before and after the treatment period was done to confirm the clinical results. Antileprotics showed very encouraging results in the treatment of rhinoscleroma where 26 out of 30 patients [86.67%] showed both clinical and histopathological improvement after treatment with antileprotic drugs for 3 months

Effect of some amino acids and the antibiotic-ZAG-9 on proteolytic activity and antibiotic productivity of streptomyces galbus

The culture medium of SGalbus was supplemented with a number of amino acidsArginine, histidine, glutamine, tyrosine, proline and valine increased the growth after 6th day of incubation, while, valine was the most effective in promoting the antibiotic productionThe highest production of protease by SGalbus was reached during cultivation in the presence of cystineEffects of the antibiotic- ZAG-9 on growth, proteolytic activity and productivity of antibiotic were also studied