Interpretation of Argyrophilic nucleolar organizer regions[AgNORS] count in cervical smears

The AgNOR staining technique for nucleolar organizer regions [AgNORs] was applied to 50 cervical smears of suspicious cases. The mean numbers of AgNORs in normal cervical cells were: superficial cells [2.3], intermediate cells [2.6], basal cells [2.5] and endocervical cells [2.4]. The mean number of AgNORs dots in mild dysplastic cells was [2.8] and of moderate, severe dysplastic cells were [3.6], [4.1], respectively, while in malignant cells was [4.0]. The AgNOR stain is useful in the differentiation between normal, dysplastic and malignant cells. No significant difference between mean number of AgNORs dots in normal and mild dysplastic cells, also between severe dysplastic and malignant cells

Cutaneous changes in diabetic foot lesion: clinicopathological study and ultrastructural changes in peripheral nerves

Forty five diabetic patients were submitted to this study. They were allocated into 2 groups: Group A comprised 30 patients with diabetic foot lesion [DFL], and group B included 15 diabetic patients without DFL as a control group. A skin biopsy from the edge of the lesion in group A and from medial border of the foot in group B were obtained. There was no significant difference between the incidence of hyperkeratosis, thick collagen, nerve lesion or vascular lesion in group A cases. However, there was high significant difference between group A and B in the incidence of cutaneous changes. Consequently, cases of group B with hyperkeratosis, thick collagen, neuropathy and vascular lesion would be considered at risk to develop DFL