Piroxicam or pethidine for analgesia after elective laparoscopic surgery

Laparoscopic surgery is commonly performed as a day case surgery procedure despite difficulties in providing adequate postoperative analgesia for all patients were examined. The analgesic utility of intramuscular piroxicam have been studied in this setting by comparing it with intramuscular pethidine, both given after induction of anesthesia in a randomized double blind study in 60 patients. Although, the analgesic effect of 2 drugs were comparable in the immediate postoperative period, piroxicam provided significantly better analgesia four hours after surgery. The recovery time taken to awake, to ambulate and for discharge were all significantly shorter after piroxicam and the unplanned admission rate also significantly less after piroxicam. Piroxicam appeared to be useful supplement for analgesia after laparoscopic surgery, providing improved analgesia as well as decreased recovery time and fewer unplanned admissions

Drug reactions

An adverse drug reaction is any response to a drug which is noxious and unintended and which occurs at doses used in man for prophylaxis, diagnosis or therapy. This definition includes idiosyncrasy, intolerance and hypersensitivity but excludes intentional or accidental poisoning, drug abuse, therapeutic failure to adhere to a prescribed regimen

clinical appraisal of a new topical antifungal cream [tioconazole] in the treatment of superficial fungal disease of the skin Suppl 3

Tioconazole 1% dermal cream is highly effective in the treatment of superficial fungal infections. The drug is safe and easy to apply. A comparative study with other antifungal medications is recommended