Congenital hepatic fibrosis in an aborted calf

An aborted female Holstein foetus with marked generalized anasarca was referred to the Excellence Centre for Ruminant Abortion and Neonatal Mortality, Ferdowsi University of Mashhad. On postmortem examination, red-tinged ascites, pale and firm liver with extreme irregularity and numerous round to oval slightly raised foci on the capsular surface were seen. Histological examination revealed widespread fibrosis, linkage of periportal areas to the central vein region and proliferation of bile ductules forming a branching network within the fibrous tissue. The lesion was diagnosed as congenital hepatic fibrosis

study on gastrointestinal helminths of camels in Mashhad abattoir, Iran

Abattoir survey was carried out to determine the prevalence of gastrointestinal helminths and the seasonal fluctuations in intestinal worm burdens and faecal worm egg counts of camel in Khorasan Razavi province in the northeast of Iran. A total of 306 dromedaries [Camelus dromedarius] in the Mashhad abattoir, in the northeast of Iran and the capital of Khorasan province were examined between October 2007 and September 2008. By coproscopy examinations, 75.1% of dromedaries were found to be harboring different types of nematod eggs. Faecal flotation revealed the presence of Nematodirus, Strongyloides, Trishuris, Marshallagia, stongyle type nematode eggs. In addition, gastrointestinal tracts of 50 camels slaughtered in the Mashhad abattoir were used for identification and count of helminths. Postmortem examinations revealed that the prevalence of helminths were Trichostrongylus probolurus [64%], Trichuris globulosa [40%], Camelostrongylus mentulatus [38%], T. colubriformis [34%], Stilesia globipunctata [30%], Nematodirella dromedarii [22%], Haemonchus longistipes [18%], Nematodirus oiratianus [16%], Cooperia oncophora [16%], Trichuris barbetonensis [10%], Parabronema skrjabini [10%], Nematodirella cameli [10%], Marshallagia marshalli [4%], Teladorsagia circumcincta [4%], Moniezia benedeni [3%], Moniezia expansa [3%] and Trichostrongylus vitrinus [2%]. Nematodirella dromedarii, Trichostrongylus probolurus, Trichostrongylus colubriformis, Cooperia oncophora, and Nematodirus oiratianus, were identified from dromedary in Iran for the first time. The pathological lesions in the affected abomasums, as well as small and large intestines, were hyperaemic and thickened mucosa with haemorrhagic foci. Histopathological examination revealed inflammatory reaction in the abomasa, flattened mucosa and villous atrophy with inflammatory reactions composed of eosinophils and lymphocytes in the intestines, respectively. The prevalence observed in the present study indicates the necessity of using an anthelmintic drug for increasing the health and productivity of camels

Gastrointestinal infection with Brachyspira spp in a filly with chronic diarrhea: a case report

An eleven month old filly was referred to the Research and Teaching Hospital of the Faculty of Veterinary Medicine at the University of Tehran. The animal presented a three-week history of diarrhea and previous treatments had failed to effect a recovery. Based on the history, clinical findings and results of laboratory investigations, it was assumed that a gastrointestinal disorder was affecting the filly. After the exclusion of other possible etiologies, Brachyspira spp. became the most likely causative agent. Despite supportive therapy in hospital, the clinical condition of the filly deteriorated over the course of eleven days and the animal died of inanition and consequent multiple organ dysfunctions. Subsequent pathological investigation confirmed a Brachyspira spp. infection of the gastrointestinal tract. This report is believed to be the first equine case of Brachyspira-associated gastroenteritis

Fatal splenic rupture caused by an atypical malignant lymphoma in a Holstein cow

Postmortem examination of a 5.5-year-old Holstein cow with history of sudden death showed a very huge spleen [120 x 45 x 10 cm] associated with severe haemoperitoneum. Histopathological findings included extensive infiltration of medium to large sized lymphocytic and lymphoblastic cells with small amounts of cytoplasm, round nuclei with coarsely granular chromatin in the spleen, and limited foci of similar cellular infiltration in the liver. This case was diagnosed as a fatal splenic rupture caused by an atypical malignant lymphoma

Experimental oleander [Nerium oleander] poisoning in goats: a clinical and pathological study

Dried ole and er leaves at single lethal dose of 110 mg/kg body weight were administered orally to five native female goats. Clinical signs of toxicosis in goats began to appear about 1 hr after receiving the ole and er and included abdominal pain, ruminal atony and tympany, frequent urination, bradycardia, tachycardia, tachyarrhythmia, depression, weakness and convulsive movement and death at the end stage. Electrocardiography revealed sinus bradycardia, sinus tachycardia, A-V dissociation, ventricular premature beats, depression of S-T segment, ventricular tachycardia and ventricular fibrillation. Four goats died within 4 to 84 hrs and one survived. Haemorrhages in varying degrees in internal organs were observed at necropsy. Histopathology revealed extensive tubular necrosis in kidneys with haemosiderin pigment in the cytoplasm of convoluted tubular cells, varying degrees of coagulative necrosis of cardiac muscle cells associated with haemorrhage and infiltration of mononuclear inflammatory cells, scattered necrosis of hepatocytes, perivascular and perineural oedema, haemorrhagic foci and ischemic cell changes in brain, congestion and oedema in lungs. Severe hyperaemia and infiltration of inflammatory cells were also observed in tissue sections of forestomachs, abomasum and different parts of the intestines

first report of abdominal mesothelioma in a ram in Iran

Primary tumours arising from the mesothelial cells lining the peritoneal cavity, mesothelioma, have been recorded in the abdominal cavity of cattle, horses, dogs and cats. Abdominal tumour masses from a five-year-old male kordi sheep were found during routine inspection at the Mashhad abattoir. At gross examination, the tumour consisted of gray-white multiple firm, sessile nodules, approximately 2.60 kg in weight. Histopathological examination revealed numerous thin papillary projections covered by cuboidal cells with large vesicular nuclei and prominent nucleoli and in some areas the neoplastic cells lined cystic spaces. Mitotic figures were few. Based on histopathological findings, the tumour was diagnosed as abdominal mesothelioma