RESUMO
In this study eighteen psoriatic patients were treated by various lines of therapy [local keratolytic, systemic methotrexate and radiotherapy] in order to evaluate the pathological changes in psoriasis under different therapies by cell counting study pre - and post-treatment. It was found that there were insignificant statistical difference in the different type of cells before and after using local therapy, while, there were statistical significant reduction in the percentage of mitotic cells after methotrexate. Also, there were very highly significant and highly significant reduction in the percentage of mitotic and resting cells respectively after radiotherapy. While, there was very highly significant statistical increase in the percentage of degenerating cells after radiotherapy