Comparison of induction and recovery charcteristics of sevoflurane and halothane in pediatric ansthesia

Forty children ASA I-II, aged 3-9 years scheduled for adenotonsillectomy were randomly divided into two equal groups [each group 20 patients] according to whether they induced and maintained with halothane and sevoflurane. The comparison was between the two groups as regards induction, recovery characteristics, hemodynamic changes as well as complications happened during induction and recovery. Anesthesia was induced using graded inhalation technique with either halothane up to 5% and sevoflurane up to 8%. Maintenance was achieved by 1.5-2% halothane and 1-4% sevoflurane. The times of induction and emergence were significantly shorter in sevoflurane as compared with halothane group. The better intubation conditions were observed in patients who received halothane anesthesia with no statistically significant difference. The hemodynamic changes were similar in both groups with improved cardiovascular profile in sevoflurane group. There was no significant difference between the two groups as regards airway complications during induction and recovery. The conclusion of the study is that sevoflurane could be used safely as an alternative to halothane in pediatric anesthesia

Perioperative evaluation of patients with liver cirrhosis

This work studied 30 patients of both sexes aged between 30-73 years, weighing between 66-95 kg undergoing upper abdominal surgical procedures under general anesthesia. The patients were randomly assigned into three categories according to Child-Pugh and Moemen classification. PT prolonged, serum creatinine and albumin level were measured compared before and after preparation. Intraoperative hemodynamics, morbidity and mortality were evaluated. In this study, it was observed that the PT prolonged and serum creatinine were decreased and albumin level was increased after preparation as compared to baseline value. Although hemodynamic changes during operation were sometimes statistically significant, this was of no clinical importance. Comparison of Child-Pugh and Moemen scores and classifications by statistical study showed a significant positive correlation between them. In the present study, the morbidity was reported by 30% in all patients within 30 days after operation. The overall mortality rate was 6.6% within 30 days after operation