Hydatid disease of liver: management of cysto-biliary communication

A prospective study of 18 cases of hepatic hydatidosis revealed a high incidence [72.22%] of cystobiliary communication and its relation to the large size of the cysts. T-tube drainage of the common bile duct was found to be an effective method in treating and/or preventing biliary fistulae. High complication rates of surgery emphasize the need for early diagnosis and use of newer, less invasive techniques in managing this disease

Surgical adjuvant chemotherapy for breast cancer: a comparison of CMF and CAF regimens

Combination chemotherapy with cyclophosphamide, methotrexate and fluorouracil [CMF] was compared with cyclophosphamide, adriamycin and fluorouracil [CAF] as adjuvant to modified radical mastectomy in primary operable breast cancer with positive axillary lymph nodes. After 18 months of study, treatment failure occurred in 10% patients in each group. The new clinical manifestations occurred locally in 75% and at distant site in 25% of relapsed patients. Long term chemotherapy produced an acceptable toxicity, thus allowing the administration of a high percentage of drug dosage. This study suggests that CMF and CAF regimens have comparable efficacy and toxicity in surgical adjuvant chemotherapy for breast cancer