RESUMO
Objective: This study was designed to analyze the effects of hexavalent chromium on histology of leydig cells of mice
Place of Study: Animal House of Zoology Department, University of the Punjab, Lahore
Materials and Methods: This experiment was performed on mature adult male albino mice, which were divided into eight groups. Control groups were designated as A1, B1, C1 and D1, whereas experimental groups A,B,C and D, received chromium [2mg/kg], i.p., as potassium dichromate on alternate days for two, four, six and eight weeks, respectively
Conclusions: Significant histological changes were recorded in the testes of treated mice, after prolonged exposure of chromium. Leydig cells were reduced in number and size, nuclei of these cells were also reduced in size and were pyknotic. The resultant decrease in size is a matter of concern in young males. In case of chronic exposure more drastic deleterious effects with appear. Future research work will add further information in this regard