RESUMO
Background: Helicobacter pylori [H. pylori] plays an important role in gastroduodenal disease. However, there are few data concerning the epidemiology of H. pylori in patients with chronic renal failure and on hemodialysis [HD] treatment
Aim of the Study: This study is aimed to determine the epidemiology of H. pylori infection in patients with end stage renal disease [ESRD] on Hemodialysis [HD]
Patients and Methods: Ninety-six patients with dyspeptic complaints were included in the study. They were divided into two groups; group one consisted of 46 patients with ESRD on HD and group two [control] of 50 patients without renal disease. All patients were subjected to upper gastrointestinal endoscopies, and gastric biopsies were obtained for histological evidence of H. pylori infection
Results: The mean age of both groups was similar. The prevalence of H. pylori among the two groups was not significantly different [45.7% Vs 48% = p>0.05]. The prevalence of duodenal ulcers was significantly higher in H. pylori positive than in H. pylori negative ESRD patients [p<0.05]. GERD was significantly lower in H. pylori positive patients in both groups [p<0.001 and p<0.01 respectively]
Conclusion: This study showed a similar prevalence of H. pylori infection in both groups. H. pylori infection in patients with ESRD is probably associated with increased risk of gastroduodenal lesions