Lipid peroxidation and gentamicin therapy in patients

The effect of gentamicin therapy on the lipid peroxidation process was studied. Thirty patients were enroled in this study, and twenty healthy individuals were served as control. The results showed that gentamicin significantly suppressed the activity of lipid peroxidation as manifested by low level of the byproduct malondialdehyde. This effect was observed when gentamicin was prescribed either therapeutically for seriously ill patients table [1] or prophylactically for the prevention of post surgical infected complications table [2]. It is concluded that gentamicin behaves as an inhibitor of lipid peroxidation beside its antimicrobial effects