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Mem. Inst. Oswaldo Cruz ; 99(1): 81-83, Feb. 2004. tab
Artigo em Inglês | LILACS | ID: lil-356448

RESUMO

The enteropathogenic role of cytotoxic necrotizing factor (CNF)-producing Escherichia coli was investigated by searching cnf genes among 2074 isolates from 200 children with and 200 without acute diarrhea in Brazil. Fourteen (7 percent) cases versus 10 (5 percent) control children carried at least one cnf positive isolate (P = 0.50) and most isolates expressed CNF type 1. DNA sequences of virulence factors of extraintestinal pathogenic E. coli (ExPEC) were detected in 78.6 percent of CNF1-producing isolates. Besides not being associated with human acute diarrhea, the CNF1-producing isolates here identified may represent potential ExPEC transitorily composing the normal intestinal flora.


Assuntos
Pré-Escolar , Humanos , Lactente , Criança , Diarreia , Escherichia coli , Infecções por Escherichia coli , Doença Aguda , Estudos de Casos e Controles , Sondas de DNA , DNA Bacteriano , Escherichia coli , Fezes
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