Correlation between Chlamydia trachomatis endocervicitis and pelvic lesions in infertile patients

Chlamydia trachomatis usually causes asymptomatic cervicitis, but infrequently it spreads upwards to involve the uterus, Fallopian tubes, or peritoneum, causing pelvic inflammatory disease and even results in infertility. In our study, we examined endocervical chlamydial antigens in infertile women and evaluated them laparoscopically thereafter according to a pelvic scoring system based on the R-AFS classification. It has been found that in patients whom were positively tested for chlamydial infection, the total pelvic score was significantly higher than in patients whom were negatively tested. When each examined area was assessed separately, however, only the tubal score was significantly higher in the chlamydia-infected patients. Our study indicated that genital infection with chlamydia trachomatis, may be responsible for infertility if it has involved the Fallopian tubes

Correlation of a simple biochemical marker and intraamniotic infection in patients with preterm premature rupture of membranes

Subclinical intramniotic infection has been associated with preterm labour and preterm premature rupture of membranes. Prompt diagnosis of subclinical intraamniotic infection is important in that it may prevent the maternal and neonatal morbidity associated with clinical chorioamnionitis. While amniotic fluid cultures are widely used to assess the microbiologic state of the amniotic cavity, results are not immediately available and are not capable of covering a wide range of organisms with different culture requirements. Rapid methods for detection of infection such as Gram stain and acridine orange stain of AF are insensitive. This study evaluated AF glucose concentration as an early parameter of intraamniotic infection. Amniocentesis for 40 patients with preterm PROM