Thermogenic Response to Fasting and Exercise in Different Aged Rats / 소아과

PURPOSE: Recently, there has been a marked increase in childhood obesity, and that has aroused social concern. Obesity increases several metabolic disease such as hypertension, diabetes, fatty liver, heart disease and the mortality rate. Complications of obesity are more closely related with the accumulation of visceral fat. Therefore, fundamental treatment of obesity Should be the reduction of body fat. Exercise is the best way to reduce body fat, especially to consume the free fatty acid released from adipocytes. However, it is anticipated that children's response to exercise could differ from adult's. This research was done to find the difference adaptations of energy metabolisms in exercises between children and adults. METHODS: Sprague-Dawley male rats were divided into a young group(two-three months old), adult group(six months old) and an old group(fifteen months old). At fed ad libitum, O2 consumption and CO2 production were measured before and after the exercise. Before and after fasting for 24 hours, O2 consumption and CO2 production were measured. After fasting for 24 hours, the blood was taken to analyse the plasma glucose and free fatty acid. RESULTS: The fasting oxygen consumption decreased only in young rats compared with that of the fed state. The fasting respiratory quotient was decreased in the young and adult rats compared with those of the fed state. The post exercise oxygen consumption was increased in the young and adult rats but not in the old rats. The post-exercise respiratory quotient was decreased only in the young rats. There was no significant change of plasma glucose and free fatty acid between fed and fasting state in the young rats, while the fasting glucose levels were increased in the adult and old rats. CONCLUSION: These results mean that the responses to fasting and exercise differ among rats of different age groups and young rats can burn fat more easily during exercise and fasting than those of the adult and old rats because of the better metabolic flexibility of young rats.

Mothers' Recognition of Childhood Obesity

PURPOSE: This study was performed to know the mothers' recognition of childhood obesity because the mothers' role is essential for management in childhood. METHODS: Seven hundred and seventy two mothers who visited pediatrics clinics in five regional cities(Daegu, Kumi, Waekan, Kyungsan and Youngchun) were include in a questionnaire survey concerning childhood obesity. The questionnaire was anonymous and filled in by the mothers themselves. RESULTS: Most of the mothers perceived childhood obesity as a serious disease. Sources of acquisition of knowledge about obesity were health programs on TV or radio(70.3%), advertisements in newspapers or magazines(44.0%) and from neighbors or relatives(20.0%) and hospitals or clinics(3.0 %). Mothers wish to acquire more knowledge about childhood obesity by health programs on TV or radio(43.8%) and hospitals or clinics(35.9%). The most common apprehensions of mothers carring out their childrens' obesity management program was psychologic stress(63.6%). If children were obese, almost all mothers wanted to treat them by various methods. CONCLUSION: For the more efficient management of childhood obesity, doctors' role in consultation and management should be emphasized.

Gastric Ulcer Due to Three Magnets Ingestion in a 37-month-old Girl / 대한소아소화기영양학회지

The accidental swallowing of foreign body is a common problem in the children. We describe the case of 37-month-old girl in whom a gastric ulcer was caused by the ingestion of three magnets. This case report demonstrates that if more than one magnet were swallowed, they should be removed even if there are no sharp edges and small size. Because the magnets will attract each other and hold the intestinal walls between them, causing necrosis and resulting in intestinal perforation or a fistula.

A case of Dubin-Johnson Syndrome / 영남의대학술지

Dubin-Johnson Syndrome is a form of benign, familial idiopathic jaundice presenting with chronic intermittentconjugated hyperbilirubinnmia and a melamin-like pigment has been found in the parenchymal liver cells. This disorder is rarely diagnosed in the neonatal period. We report a case of Dubin-Johnson syndrome presenting with neonatal cholestasis.

A case of Dubin-Johnson Syndrome / 영남의대학술지

Dubin-Johnson Syndrome is a form of benign, familial idiopathic jaundice presenting with chronic intermittentconjugated hyperbilirubinnmia and a melamin-like pigment has been found in the parenchymal liver cells. This disorder is rarely diagnosed in the neonatal period. We report a case of Dubin-Johnson syndrome presenting with neonatal cholestasis.