Effect of feeding BHC on the biochemical parameters of blood in rabbits

Studies were made by feeding 25 mg per kg body weight of BHC to rabbits daily for twelve weeks. BHC in the blood increased progressively without affecting blood pH. The levels of glucose, cholesterol, total proteins and creatinine increased while that of urea decreased in the blood of treated animals. The differences among the control and treated rabbits for these parameters were highly significant as every one microgram per ml accumulation of BHC in the blood, affected a corresponding increase of 1.82 mg/dl glucose, 2.618 mg/dl of cholesterol, 0.02 g/dI of total proteins and 0.13 mg/dl of creatinine, while a ' decrease of 0.105 mg/dl of urea was observed. The feeding of BHC, therefore, affected these vital biochemical parameters significantly

Effects of oral administration of BHC on the blood enzymes of rabbits

The effects on the blood enzymes of rabbits were ascertained by daily oral administration of 25 mg BHC per kg body weight for twelve weeks. The amount of BHC in the blood increased progressively and reached a maximum of 86.012 /Jg per ml. The levels of enzymes were elevated though there was a nonsignificant increase in the pH value of the blood of the treated group. An increase of 0.323 and 0.587 units of acid and alkaline phosphatases, respectively, was observed for every one microgram per accumulation of BHC in the blood. The analysis of blood for enzymes AST and ALT, indicated that one microgram of blood BHC increased the two enzymes by 0.344 and 0.697 units. The treated group of rabbits showed many behavioural abnormalities

Incidence of endrin residues in cucumber and its effects on the biological system of rats

The residue levels of Endrin were estimated in cucumber [Cucumis sativus] samples showed that 35.5% contained endrin residues ranging from 304.3 to 669.4 ug per 100 g vegetable. The calculated daily consumption of endrin by human population, thus falls between 13.1 and 28.7 ug per kg body weight. The disappearance of endrin in cucumber was also noted after spraying the insecticide in an experimental field. The residues persisted upto 14 days. Female albino rats receiving 28.7-ug endrin per kg body weight, accumulated endrin in their livers [5.47 ug/g] and its amount in the blood increased progressively [15.21 ug/ml] upto 28 days. The enzymes AST and ALT increased progressively, but no endrin was excreted in the faeces. The growth rate of rats as well as principal body organs, were adversely affected by the oral administration of the insecticide