RESUMO
Purpose: Comparative study of intraoperative and postoperative complications, visual outcomes, and cost?effectiveness between conventional and 4?mm manual small?incision cataract surgery with MVR blade. Methods: In total, 600 patients having nuclear sclerosis grade I朓V were operated under peribulbar anesthesia and were divided into two groups of 300 each. In group A (300), conventional small?incision cataract surgery was done, whereas in group B (300), 4?mm manual small?incision cataract surgery was performed through a 4?mm sclerocorneal tunnel. A wire vectis was passed through the 4?mm incision below the nucleus to stabilize it, and a 20?G MVR blade was introduced from 11o抍lock limbus and nucleus was bisected into two halves, which were removed through main incision. Cortical wash was given, and foldable IOL was implanted. Intraoperative and postoperative complications between the two groups were compared. Postoperative visual outcome and surgically induced astigmatism between the two groups was studied. Results: The most common intraoperative complication was hyphema (11.33%) and irido?dialysis (8.00%), whereas postoperatively, striate keratopathy (36.33%) and hyphema (19.33%) were common. Short?term complications such as striate keratopathy, hyphema, and irido?dialysis were significantly more in group B, and long?term results in terms of visual outcome and surgically induced astigmatism were significantly less in group B. Conclusion: Although intraoperative and short?term postoperative complications were observed more in 4?mm manual small?incision cataract surgery, it was found to be more effective in terms of surgically induced astigmatism and final visual outcome. In addition, it is cost?effective as compared to phacoemulsification.
RESUMO
Ayurveda-The traditional medicinal science in India has holistic approach and practiced widely in the subcontinent. Large parts of the Ayurvedic drugs are heromineral preparations. These preparations are broad spectrum as far as its indications are concerned. Definite mode of action of these drugs are inexplicable. Vyadhividhwansana Rasa is an herbomineral preparation used for treating acute fever, interrupted fever, fever of unknown origin, ascites, splenomegaly, colic pain, Vata vyadhi, Aama jwara (first stage of fever) and Vishama jwara (irregular fever). In view of its therapeutic indications an antimicrobial study was designed to ascertain its probable mode of action. The present study aims to evaluate the antimicrobial activity of Vyadhividhwansana Rasa against test organisms at different concentration. Vyadhividhwansana Rasa was prepared as per Ayurvedic texts. Positive control Streptomycin [5mg(w/v)] and negative control 20% dimethyl sulfoxide (DMSO) were prepared. Solution of Vyadhividhwansana Rasa were prepared in three concentrations at 50 mg/ml, 100 mg/ml and 150 mg/ml in DMSO and was tested for its antimicrobial activity against Escherichia coli, Streptococcus pyogenes, Staphylococcus aureus, Pseudomonas aeruginosa and Salmonella typhi by agar-well diffusion method. The measured Inhibition Zone ranged from 4-34 mm for all the sensitive bacteria. All the bacteria except Salmonella typhi were found Susceptible (S) against Vyadhividhwansana Rasa compared to standard. Salmonella typhi was found Intermediate sensitive (I). The antimicrobial activity of the extracts increased when the solution is more concentrated.