RESUMO
Present study was planned to compare xenogenic decellularized bubaline diaphragmatic scaffold with synthetic polygalactin and polypropylene composite mesh for repair of perineal hernia in dogs. Twelve dogs suffering with perineal hernia were randomly divided in to two equal groups. In group I perineal hernioplasty was done with Synthetic polygalactin and polypropylene composite mesh while in group II, with decellularized bubaline diaphragmatic scaffold (dBDS). Mean surgical time was 59.17 ± 14.04 and 57.50 ± 6.15 minute in group I and II respectively. Swelling, redness and warmth increased significantly (p<0.05) on day 3 in both the groups. In group II initially significantly (p<0.05) increased exudation was observed on day 3 which reduced gradually. Degree of pain after surgery was significantly (P<0.05) decrease on day 3 in both the groups. Neutrophil count was significantly (p<0.05) increased and correspondingly lymphocyte count significantly (p<0.05) decreased on day 7 in group I while in group II no significant difference within the group was observed. Colour Doppler ultrasonographic examination revealed no vascularization on 0 day in both the groups. Neovascularization was observed on day 30 in group I and day 14 in group II on Colour Doppler ultrasonographic examination. It was increased on day 90 in both the groups. The complication encountered in the present study includes local seroma, suture dehiscence due to self mutilation, constipation and fistula formation. Decellularized bubaline diaphragmatic scaffold was well accepted by all the animals and showed less complication than synthetic mesh