RESUMO
Present study was carried out to evaluate oxidant-antioxidant status and effect of hemodialysis in acute and chronic renal failure. Serum MDA levels increased while serum SOD found decreased significantly. This study indicates the existence and increased production of an oxidizing stress resulting from hemodialysis and disturbance in antioxidant enzyme system.
Assuntos
Adulto , Estudos de Casos e Controles , Feminino , Sequestradores de Radicais Livres/sangue , Humanos , Injúria Renal Aguda/sangue , Falência Renal Crônica/sangue , Peroxidação de Lipídeos , Masculino , Malondialdeído/sangue , Pessoa de Meia-Idade , Diálise Renal/efeitos adversos , Superóxido Dismutase/sangue , Resultado do TratamentoRESUMO
Serum lipids and lipoproteins were assessed in sixty leprosy and forty age and sex matched healthy controls. The study subjects included cases of LL with reactions, LL without reactions, BL with reactions, BL without reactions, BT and TT types of leprosy. The levels of serum phospholipids, triglycerides, total cholesterol, LDL and VLDL fractions were significantly decreased in leprosy patients compared to control subjects. The levels of serum HDL cholesterol and HDL fraction were significantly elevated in leprosy patients. Maximum elevation in serum HDL cholesterol level and HDL fraction and maximum reduction in the levels of serum phospholipids, triglycerides, total cholesterol and LDL and VLDL fractions were observed in lepromatous leprosy (LL) patients with reactions.