RESUMO
The present work represented a comparative quantitative study of the respiratory ciliary mucosa in six cases of primary ciliary dyskinesia [PCD], six cases of secondary ciliary dyskinesia [SCD] and twelve cases of normal non-inflamed mucosa as a control group. Light microscopy, ultrastructure constituents and deviation angle of the cilia were studied. There was no difference by light microscopy, while the differences in the ciliary constituents were statistically insignificant. It was found that the mean ciliary deviation angle in both the control and SCD group was less than 30C; while in PCD group, it was 43 degrees. The pattern of the histogram can help in the diagnosis. The interpretation of the different ultrastructural findings should be associated with the deviation angle along with the history of sinusitis, otitis media and respiratory tract infection since birth
Assuntos
Humanos , Masculino , Feminino , Microscopia Eletrônica , Microscopia , Otite Média , Sinusite , Infecções RespiratóriasRESUMO
Ovarian metastasis from colorectal carcinoma frequently mimics primary ovarian carcinomas. The present study was performed to find possible histopathological criteria helpful in the differential diagnosis. Twelve cases of primary colonic adenocarcinoma with unilateral [5/12] or bilateral [7/12] ovarian metastasis as well as 12 cases of primary ovarian carcinoma of unilateral [7/12] and bilateral [5/12] were included in this study. Both were evaluated clinicopathologically, ultrastructurally and immunohistochemically including CK-7 and CK-20. The integration of the clinicopathological and immunohistochemical findings was very helpful, while electron microscopy had less value in the determination of primary ovarian carcinoma from ovarian metastasis of colonic origin. Bilaterally, extrapelvic spread, high mitotic index, garland, segmental and dirty necrosis, positivity for CK-20 and lack of CK-7 immunoreactivity favored the diagnosis of ovarian metastases from colon carcinoma