RESUMO
A systematic study has been carried out to explore the water quality index of ground water of various locations of Gulbarga city. Ten water samples from tube wells, open wells and hand pumps at various locations were collected using standard procedural methods and analyzed for pH, nitrate, turbidity, total hardness, alkalinity, fluoride, sulphate, sulphide, COD and DO. Biological examinations were extensively carried out on each sample using known standard methods. In this study overall water quality of Gulbarga city is very poor and unsuitable for drinking purposes. Present study recommends that the top priority should be given to water quality monitoring and indigenous technologies should be adopted to make water fit for drinking after treatment such as desalination and defluoridation.
RESUMO
Binding of arylsulphatase Β to isolated rat liver lysosomal membrane has been studied at 37°C. The binding is strongly pH dependent and is governed by ionic strength of the medium. Experimental evidence is given for the ability of the enzyme to dissociate from the firmly formed membrane enzyme complex. The dissociation rate is greatly accelerated by raising the buffer molarity. Neuraminidase treatment of the membrane causes significant reduction in its binding ability to the enzyme. This suggests that sialic acid groups participate, presumably by maintaining surface negativity of the membrane, at a stage of enzyme membrane interaction process which precedes the internalization of the lysosomal enzymes in the lyso omes.