Serum testosterone and aggression in schizophrenics and substance abusing subjects

This study had been carried out in psychiatric department of Zagazig University Hospital and Al Azazy Mental Hospital with the aim of studying the association between serum testosterone levels and aggression in some psychiatric disorders. 24 schizophrenics and Substance abusing who presented to the outpatient clinic with aggressire behaviour were subjected to the following; DSMII, R and clinical diagnosis, Brown aggressive scale and also measurement of free and total testosterone and sexhormone binding globulin [SHBG] by radioimmuno- assay and Enzyme immuno- assay teahniques. The results showed that substance abusing males had significautly higher serum levels of total and free testosterone than schizophrenics and controls. Also among schizophrenics the serum level of this hormone decreased significantly more with age compared to the other two groups, and correlated negatively with the duration of neuropleptic drug usage. The results also showed that the aggressive behavior of the schizophrenics were significantly lower than that of the drug abusing subjects, however there was no significant correlations between serum testosterone levels and the intenesity of aggression in either the schizophrenics or the substance abusing subjects

Extended pyelonephrolithotomy [modified resnick S technique] for the management of stagging renal stones

Seventeen patients with stagging renal stones extending mainly to lower calyces with or without multiple calyceal stones or extensions, 13 with intrarenal pelves were included in our study. We used a combination of Gil- vernet [s extended pyelolithotomy technique and Resnick[spyelo-nephrototomy technique. None of our cases needed blood Transfusion, none had serious post- operative bleeding and none developed hypertension during a follow- up period of 3 years. Only 1 patient had residual calyceal stone that was managed later by ESWL. We concluded that this is a safe operative technique for the management of some stanging renal stones, with low rate of complications.

hemodynamics of sexual dysfunction following nerve sparing Radical cystoprostatectomy

Fourteen patients with invasive bladder cancer underwent penile duplex scanning and dynamic infusion cavemosometry preoperatively to assess arterial and venous hemodynamics. Nine of these patients were impotent after nerve sparing Radical cystoprostatectomy and had repeated duplex scanning and cavemosornetry six months postoperatively. On penile duplex all 9 patients had arterial insufficiency on at least one side in-spite of individual vesical arteries ligation. On dynamic cavernosometry. 2 patients had the criteria suggestive of corporoveno-occlusive dysfunction. We concluded that impotence following nerve sparing radical cystoprostatectomy is predominantly arterial in nature. The possible causes and points of technique are discussed