Subclinical cardiac dysfunction in children with vitamin D deficiency rickets: biochemical and echocardiographic study

Twenty-four children with a clinical evidence of moderately severe vitamin D deficiency rickets and ten healthy children of matched age and sex, as a control group, were included in this study. Serum profile of vitamin D status was studied. Echocardiographic assay of fractional shortening [FS] and right ventricular systolic time interval [RPEP/RVET] were done for all cases and controls. Regression analysis revealed that low serum magnesium and high LDH were the predictors of decreased left ventricular systolic function