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2.
Yonsei Medical Journal ; : 242-248, 2003.
Artigo em Inglês | WPRIM | ID: wpr-73202

RESUMO

We assessed whether acid fast bacilli (AFB) determination in gastric lavage (GL) and bronchial lavage (BL) contributes to diagnosis in cases radiologically suggestive of pulmonary tuberculosis but with either negative AFB in sputum or the inability to expectorate sputum. Of 129 cases recruited for the study, 22 were excluded due to evaluation as inactive disease or non-tuberculosis disease. The remaining 107 cases were evaluated in 2 groups. Group A consisted of 49 patients that could not expectorate sputum and from whom GL was obtained. In group B, BL was performed in 58 patients that had negative sputum smear. Smear positivity was 61.2% (30/49) and culture positivity was 30.6% (15/49) in group A, 51.7% (30/58) and 81% (47/58), respectively, in group B. Thirteen cases, in whom AFB could not be detected microbiologically but who were radiologically strongly suggestive of tuberculosis, were regarded as tuberculosis according to 'from treatment to diagnosis' criteria. In conclusion, detection of AFB positivity in the diagnosis of tuberculosis is important in terms of early initiation of treatment and detection of resistant bacilli. Therefore, we suggest that it would be helpful to obtain GL in cases where the patient is unable to expectorate sputum, and perform BL in cases with negative sputum smear.


Assuntos
Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Lavagem Broncoalveolar , Lavagem Gástrica , Mycobacterium tuberculosis/isolamento & purificação , Reação em Cadeia da Polimerase , Tuberculose Pulmonar/diagnóstico
3.
Yonsei Medical Journal ; : 169-173, 2003.
Artigo em Inglês | WPRIM | ID: wpr-26462

RESUMO

Pneumoconiosis was diagnosed by open lung biopsy in two dental technicians who had interstitial lung disease. Mineralogical analysis was performed to investigate the origin of the dust that had been inhaled. A marked accumulation of silicon and phosphorus was found in both cases. The hard metals chromium and cobalt were also found. Dental technician's pneumoconiosis is a complex pneumoconiosis in which such dust and hard metals may play a role.


Assuntos
Adulto , Humanos , Masculino , Técnicos em Prótese Dentária , Pulmão/patologia , Doenças Pulmonares Intersticiais/diagnóstico , Minerais/metabolismo , Doenças Profissionais/diagnóstico , Pneumoconiose/diagnóstico , Radiografia Torácica , Tomografia Computadorizada por Raios X
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