RESUMO
Crude methanolic extract of roots, aerial parts and its subsequent fractions of Ferula narthex Boiss were tested for antibacterial, anti-fungal and phytotoxic activities. Crude methanolic extract of roots and its fractions showed significant antibacterial effect against P.aeruginosa [86.95%, 73.91, 69.59, 78.26 and 73.91%] represented by percent inhibition except ethyl acetate [EtoAc] fraction. The EtoAc fraction of roots and aerial parts showed significant activity against E. coli [80%], S. typhi [81.2 and 81.25%] and S. pneumoniae [80%]. The n-hexane, chloroform and aqueous fractions of aerial parts showed significant activity against P. aeruginosa [78.26, 69.56 and 73.91%]. Following fungal strains [T. longifusus, C. albicans, A. flavus, M. canis, F. solani, C. glabrata] were also used for anti-fungal activity. Among tested samples only crude methanol extract of roots, n-hexane and chloroform fraction showed moderate antifungal activity against M. canis [40, 35 and 30%] represented by percent inhibition. The remaining fractions showed no effect on tested fungi. Different oils fractions were also tested against above fungal strains. Fraction I, II and V showed mild to moderate activity against M. canis [40, 40 and 25%]. Phytotoxic effect of tested samples of roots, aerial part and its fractions showed concentration dependent growth inhibition. Maximum phytotoxic effect was noted for n-hexane and aqueous fraction [50% growth inhibition]. The remaining tested samples showed mild effect on growth of Lemna minor plant