Pattern of gastrointestinaI cancers in South Eastern Region of Yemen

Primary gastrointestinal malignancies are more common than other malignancies among Yemeni patients. This study was conducted retrospectively with the aim of studying the pattern of primary gastrointestinal malignancies among Yemeni patients attending the Oncology Department of Al-Gamhouria Teaching Hospital, Aden, for the period from Jan. 2001 to Dec. 2004. During the four-year study period, a total of 289 patients with primary gastrointestinal cancers were reported, 173 [59.9%] were males and 116 [40.1%] were females [p=0.0002]. The ratio of male to female was 1.49:1. The age ranged from 4 to 90 years, with a mean of 55.6 +/- 13.4 years. Statistically, there is a significant difference between the means of ages of different sites of primary gastrointestinal cancers [p=0.0000]. The common types of primary gastrointestinal cancers in this study include coloreetal [30.4%] and gastric cancers [29.1%], followed by hepatic [14.9%], pancreatic [12.8%], and esophageal cancers [10.0%]. Lower percentages were noted in small intestinal cancer [2.1%] and gall bladder cancer [0.7%]. Higher percentage of primary gastrointestinal cancer was seen in the age 40 years [259 patients, 89.6%]. Females were affected more than males [60.0% and 40.0% respectively] in the younger age of >/= 40 gears, whereas in the age of 40 years and more, males were affected more than females [62.2% and 37.8% respectively]

antibiotics have a role in the conservative management of appendix mass?

Management of acute appendicitis is strictly surgical but acute appendicitis presented as appendix mass could be treated in different ways including using antibiotic treatment regime but these options remains controversial. The aim of this study was to evaluate the role of antibiotic in the conservative management of appendix mass. The medical records of 1051 patients diagnosed as acute appendicitis at two different teaching hospitals in in Yemen, have been reviewed for the purpose of this study. 516 cases collected from Kuwait University Hospital, [K.U.H.] Sanu'a [between Jan 2005 to Dec 2007] and 535 cases collected from Ibn Sina Teaching Hospital, [ISTH]. Mukalla, [between Jan 2007 to Dec 2007]. It has been found that 893 cases had urgent operation, and 98 patients diagnosed as suspected non obstructive acute appendicitis and got recovered completely with conservative treatment. On the other hand 60 cases, [5.7%], presented with appendix mass, and have been treated conservatively by distributing them randomly into two selected groups, group A treated with rest + antibiotic, group B treated with rest only and results analyzed prospectively The 35 appendix mass cases treated at K.U.H, represent [7.5%], cases distributed as Group A, had an average hospital stay of Sdays [ranging from3-7], while group B, had stayed an average of 6.5 days [ranging from3-ll]. 25 appendix, mass cases represent 5.1% at I.S.T.H. Group A. had an average hospital stay of 5.5 days [3-8], while group B, had an average of 8 days [3-20]. the proportion of appendix mass presented with pyrexia in both groups were 41.6%. two cases reported at I.S.T.H with signs and symptoms of recurrent sub acute appendicitis and palpable residual appendix mass, both from group A, refused operation and were treated conservatively with the same regime [antibiotics+ rest] signs and symptoms subsided in few days and discharged. Other complications such as abscess formation or spreading peritonitis were absent. Interval appendicectomy; all patients were advised to come back in 6 weeks for elective appendicectomy. 6 cases reported at K.U.H, and only 2 at I.S.T.H. All were free from signs and symptoms and they had operation Conservative treatment for appendix mass is effective and safe, antibiotic, might shorten the resolution time but not essential. Complications is only 3% and represented by recurrent sub acute appendicitis, which responded to conservative treatment. Interval appendicectomy is probably unnecessary and should be reserved for cases with recurrent of signs and symptoms only