Magnesium Increases the Protective Effect of Citicoline on Aluminum Chloride-induced Cognitive Impairment

Objective@#Alzheimer’s disease is a popular neurodegenerative disorder which is growing in the elderly people. Exposure to environmental pollutant like aluminum could trigger or accelerate its involved mechanisms like tau phosphorylation. The current study will evaluate the effect of alone or co-administration of Citicoline or/and magnesium on the aluminum chloride induced memory impairment. @*Methods@#Male albino mice were randomly divided into different groups (n = 7). Memory impairment was induced via orally administration of 300 mg/kg Aluminum Chloride for 28 days. Based on respective group, animals received 100, 250, 500 mg/kg of Citicoline or 50, 100, 150 mg/kg of Magnesium sulfate (MgSO4), intraperitoneally. In co-administration, 50 mg/kg of MgSO4 injected concomitantly with 100, 250, or 500 mg/kg of Citicoline. Rivastigmine (2 mg/kg intraperitoneally) was used as a positive control. Memory was evaluated using the Object Recognition Task (ORT) and Passive Avoidance Test (PAT). @*Results@#The studied doses of Citicoline or MgSO4 when administered individually showed significant increase in the discrimination index in ORT and latency time in the PAT compared to the Aluminium chloride (AlCl3) treated group. Concomitant injection of 50 mg/kg MgSO4 with the different doses of Citicoline strongly increased the above indices values in comparison to each alone. @*Conclusion@#The findings show, individual administration of Citicoline or MgSO4 inverted the AlCl3-induced memory impairment in a dose independent manner. The addition of MgSO4 to the Citicoline showed a synergistic effect in the PAT and likely additive effect in the ORT.

Protective Effects of Citicoline and Benfotiamine Each Alone and in Combination on Streptozotocin-induced Memory Impairment in Mice

Objective@#Diabetes mellitus is associated with cognitive disorders such as Alzheimer’s disease. Studies have shown that citicoline and benfotiamine can improve memory and learning through different mechanism of actions. The aim of this study was to compare the individual effects of benfotiamine (100, 200, 300 mg/kg) and citicoline (50, 100, 250, 500 mg/kg, gavage) and their co-administration on memory impairments in diabetic mice. @*Methods@#Diabetes was induced by a single dose of streptozotocin (STZ, 140 mg/kg, intraperitoneal) and benfotiamine and/or citicoline were administered for three weeks. Memory was evaluated using the object recognition task (ORT) and passive avoidance test (PAT). @*Results@#Results from ORT shows that citicoline at 50, 100, 250, and 500 mg/kg and benfotiamine at 100, 200, and 300 mg/kg and their combination (benfotiamine at 100 mg/kg added to citicoline at 50, 100, and 250 mg/kg) are equally effective in reversing the memory loss induced by STZ (p ＜ 0.001). PAT results demonstrate that citicoline at 100, 250, and 500 mg/kg and benfotiamine at above doses did not improve the latency time when administered separately, but benfotiamine at a fixed dose of 100 mg/kg in the presence of citicoline at 50, 100, and 250 mg/kg increased the latency time and improved memory significantly. @*Conclusion@#In conclusion, in PAT, co-administration of benfotiamine and citicoline was more effective than either alone in improving memory. Regarding ORT, although benfotiamine added to citicoline improved memory notably, the difference between combination therapy and single-drug therapy was not considerable.

The effect of ginger and metoclopramide in the prevention of nausea and vomiting during and after surgery in cesarean section under spinal anesthesia

OBJECTIVE: Postoperative nausea and vomiting is one of the most common side effects after anesthesia in surgeries, such as cesarean section. This study aimed to investigate the effect of ginger and metoclopramide in the prevention of nausea and vomiting during and after cesarean section.METHODS: This clinical trial was conducted on 180 patients aged 18–40 years who underwent cesarean section under spinal anesthesia. The first group received 10 mg of metoclopramide via intravenous injection (metoclopramide group), and the second group received 1 g of oral ginger (ginger group) half an hour before spinal anesthesia. The frequency and severity of nausea and vomiting during surgery and at 2, 6, 12, and 24 hours postoperatively were compared in both groups. To analyze the results, the t-test, chi-square test, and Mann-Whitney test were used.RESULTS: There was no significant difference in the frequency of nausea and vomiting between the 2 groups during operation, 2 hours and 6 hours after surgery (P=0.182, 0.444 and 0.563 respectively). The severity of nausea and vomiting was also similar in the 2 groups (P=0.487 and 0.652 respectively); however, the metoclopramide group had a lower systolic blood pressure (P<0.001; df=2.176; f=18.66) and mean arterial pressure (P<0.001; df=2.176; f=6.36) than the ginger group.CONCLUSION: The results revealed that ginger reduced nausea and vomiting to the same extent as metoclopramide in patients undergoing cesarean section.TRIAL REGISTRATION: Iranian Center for Clinical Trials Identifier: IRCT201611028611N3

Comparison of the effect of vitamin E, vitamin D and ginger on the severity of primary dysmenorrhea: a single-blind clinical trial

OBJECTIVE: Dysmenorrhea is one of the most common problems for women, especially during their reproductive age. Various studies have examined the effects of vitamins D and E and ginger supplements. This study aimed to investigate the individual effects of each of these supplements on dysmenorrhea. METHODS: This single-blind clinical trial was conducted in 2016 on students aged 18 to 25 years who complained of mild to severe dysmenorrhea. The participants were randomly assigned into 4 groups: vitamin D, vitamin E, ginger, and placebo. The effects of the supplements on the severity of dysmenorrhea were evaluated in 2 successive cycles using the visual analog scale (VAS) and a questionnaire. RESULTS: Initially, 240 female students were enrolled in the study; thereafter, 40 students were excluded from the study owing to follow-up loss. The average VAS score for dysmenorrhea in the entire study population was 7.13±0.80 before the intervention; the mean VAS score after the first and second months of supplement use was 5.37±1.51 and 4.93±1.48, respectively. The highest reduction in pain severity was observed in the ginger group (F=74.54, P<0.001). CONCLUSION: Vitamin D, vitamin E, and ginger significantly reduced the severity of dysmenorrhea, with ginger having the most significant effect followed by vitamin D and vitamin E. Given the low risk of these supplements, more studies must be conducted on their use as opposed to analgesics.

Exploring neighborhood inequality in female breast cancer incidence in Tehran using Bayesian spatial models and a spatial scan statistic / 한국역학회지

OBJECTIVES: The aim of this study was to explore the spatial pattern of female breast cancer (BC) incidence at the neighborhood level in Tehran, Iran. METHODS: The present study included all registered incident cases of female BC from March 2008 to March 2011. The raw standardized incidence ratio (SIR) of BC for each neighborhood was estimated by comparing observed cases relative to expected cases. The estimated raw SIRs were smoothed by a Besag, York, and Mollie spatial model and the spatial empirical Bayesian method. The purely spatial scan statistic was used to identify spatial clusters. RESULTS: There were 4,175 incident BC cases in the study area from 2008 to 2011, of which 3,080 were successfully geocoded to the neighborhood level. Higher than expected rates of BC were found in neighborhoods located in northern and central Tehran, whereas lower rates appeared in southern areas. The most likely cluster of higher than expected BC incidence involved neighborhoods in districts 3 and 6, with an observed-to-expected ratio of 3.92 (p < 0.001), whereas the most likely cluster of lower than expected rates involved neighborhoods in districts 17, 18, and 19, with an observed-to-expected ratio of 0.05 (p < 0.001). CONCLUSIONS: Neighborhood-level inequality in the incidence of BC exists in Tehran. These findings can serve as a basis for resource allocation and preventive strategies in at-risk areas.

Exploring neighborhood inequality in female breast cancer incidence in Tehran using Bayesian spatial models and a spatial scan statistic / 한국역학회지

OBJECTIVES: The aim of this study was to explore the spatial pattern of female breast cancer (BC) incidence at the neighborhood level in Tehran, Iran.METHODS: The present study included all registered incident cases of female BC from March 2008 to March 2011. The raw standardized incidence ratio (SIR) of BC for each neighborhood was estimated by comparing observed cases relative to expected cases. The estimated raw SIRs were smoothed by a Besag, York, and Mollie spatial model and the spatial empirical Bayesian method. The purely spatial scan statistic was used to identify spatial clusters.RESULTS: There were 4,175 incident BC cases in the study area from 2008 to 2011, of which 3,080 were successfully geocoded to the neighborhood level. Higher than expected rates of BC were found in neighborhoods located in northern and central Tehran, whereas lower rates appeared in southern areas. The most likely cluster of higher than expected BC incidence involved neighborhoods in districts 3 and 6, with an observed-to-expected ratio of 3.92 (p < 0.001), whereas the most likely cluster of lower than expected rates involved neighborhoods in districts 17, 18, and 19, with an observed-to-expected ratio of 0.05 (p < 0.001).CONCLUSIONS: Neighborhood-level inequality in the incidence of BC exists in Tehran. These findings can serve as a basis for resource allocation and preventive strategies in at-risk areas.

Investigation of the impact of QEEG-based biofeedback on attention and behavioral features in young male adolescents with ADHD

Introduction: Attention Deficit/Hyperactivity Disorder [ADHD] is a disorder of neurobiological behavioral system. This disorder includes features such as attention deficit, impulsivity, and chronic, disproportionate-with-growth hyperactivity which reduce the child's ability to regulate, control, organize his behavior and cause attention deficit in activity of daily living [ADL]. ADHD is one of the most common childhood disorders. The aim of this study was to investigate the effect of QEEG-based biofeedback on behavioral and attention factors of 7 to 14 year-old boys diagnosed with ADHD

Method: 40 boys diagnosed with ADHD were randomly assigned into the experimental and control groups. Integrated Visual and Auditory [IVA] test and Children's Behavioral Check List [CBCL] were used before the treatment and after 8 intervening weeks of treatment in both groups. Moreover, the brain mapping [QEEG] of the experimental group was used to design a treatment protocol. The experimental group received 24 sessions of neurofeedback therapy three times a week. The acquired data was analyzed using the Analysis of Covariance [ACNOVA]

Results: Our findings demonstrated a significant difference in test results between the experimental and control groups upon IVA and CBCL tests following the neurofeedback intervention. Moreover, there was a significant difference between pre- and post-tests in the neurofeedback group. Interaction effect was insignificant at the time

Conclusion: Results of the present study showed that neurofeedback can bring significant improvements in attention factors especially, sustained attention and children's externalizing behaviors. As such, neurofeedback may be considered as one of the therapeutic modalities used along with core therapies and medication, though, more research is needed to compare the clinical effects of different treatment protocols with one another

impact of chronic low backpain on daily occupations: a qualitative study in Iranian context

Objectives: Low back pain is one of the main health problems which affect many people worldwide

The daily course of life is highly disrupted due to the chronic back pain problem. This sudy aims to explore the occupational performance of individuals with chronic low back pain

Methods: Fifteen people with chronic low back pain were included in this sludy using purposeful sampling. The participants were interviewed, and a qualitative content analysis was employed to analyze the data

Results: The three main resulted themes were: 1] Occupational disturbance because of low back pain; 2] Difficulty in moving around and remaining in any given position; and 3] Permanent mind struggle owing to back pain. People with chronic low back pain experience difficulty in all areas of daily occupation including self-care, work, and leisure, plus having trouble with being physically active and being persistent in certain positions. Furthermore, mind struggle with back pain which implies preoccupation with back pain in addition to fear of movement are other findings of present study

Discussion: Chronic low back pain greatly influences the daily occupations of individuals. Mind slruggle with back pain, which implies preoccupation with back pain, in addition to the fear of movement are significant findings of the present study. Occupational therapists can play an important role in re-engagement of people with chronic low back pain in their daily occupations

Neurofeedback effect on perceptual-motor skills of children with adhd

Objectives: This Study investigates the impact of neurofeedback on perceptual-motor skills of 5 to 12 years old children with Attention Deficit Hyperactive Disorder [ADHD]

Methods: In this clinical Study, 40 children between the ages of 5-12 years, who were patients of the Tavanesh Clinic and diagnosed with ADHD, were randomly chosen and divided into two groups of control and test. 20-neurofeedback intervention sessions were performed The tools utilized in this Study included Bruninks-Oseretsky Tesl of Motor Proficiency and Child behavior checklist [CBCL] survey questionnaire. For evaluation after the intervention, Bruninks-Oseretsky TeSt of Motor Proficiency scale for children, along with CBCL questionnaire surveys were asked to fill up by the participants' mothers

Results: After the intervention, the analysis of the scores in all perceptual-motor skills showed significant differences in both groups, but no significant difference was observed in the subteSt of Strength. The CBCL survey questionnaire revealed that the average scores on attention disorder, aggression, lack of attention and hyperactivity, externalizing and general problems in the test group is significantly less than that of the control group. However, in the confrontational behavior [internalization], there was no Statistically significant difference between the test and control groups

There was a correlation between the change of motor skills and change of behavioral patterns in ADHD children

Discussion: Neurofeedback intervention can have positive effects on improving the perceptual-motor skills of children with ADHD

In vivo Kinematics of the Knee after a Posterior Cruciate-Substituting Total Knee Arthroplasty: A Comparison between Caucasian and South Korean Patients

PURPOSE: This study compared in vivo kinematic differences between Caucasian and South Korean patients after a posterior-substituting total knee arthroplasty (PS-TKA). MATERIALS AND METHODS: In vivo motions of 9 Caucasian and 13 South Korean knees with a PS-TKA during weight bearing single leg lunge were determined using a dual fluoroscopic imaging technique. Normalized tibiofemoral condylar motions and articular contact locations were analyzed. RESULTS: Femoral condylar motions of the two groups showed a similar trend in anteroposterior translation, but the South Korean patients were more anteriorly positioned than the Caucasian patients at low flexion and maximal flexion angles in both medial and lateral compartments (p<0.05). Mediolateral femoral condyle translations were similar between the two groups. For tibiofemoral articular contact kinematics, the South Korean patients had significantly more anterior contact locations at the medial compartment at low flexion angles, and more lateral contact locations at the lateral compartment at 0° and 90° flexion compared to the Caucasian patients (p<0.05). The South Korean patients had significantly larger distances between the medial and lateral contact locations at 60° and 90° flexion compared to the Caucasian patients (p<0.05). CONCLUSIONS: The study revealed that while the Caucasian and South Korean knees had similar femoral condylar motions, after PS-TKA the South Korean patients showed different articular contact point kinematics compared to the Caucasian patients.

[Is alopecia a clinical symptom in Kawasaki disease?]

A 20-months-old infant was admitted with prolonged fever, bilateral non-purulent conjunctivitis, strawberry tongue, lip cracking and maculopapular rash. Left branch coronary aneurysm formation was detected in Color-Doppler echocardiography. The diagnosis was Kawasaki disease. After 6 weeks, he had alopecia totalis. Although, alopecia areata has been seen in Kawasaki disease, but alopecia totalis is very rare with unknown etiology

Satisfaction of Iranian medical universities' faculty members towards holding Shahid Motahari annual educational festival

Introduction: Shahid Motahari Annual Educational Festival aims to improve the quality of medical education in the Islamic Republic of Iran, and has held since 2008. The present study was performed to determine the satisfaction level of Iranian medical universities' faculty members about holding Shahid Motahari Annual Educational Festival during the past six years, from 2008 to 2014

Methods: This cross-sectional study was conducted on 473 faculty members [FMs] including deputies and educational administrators, managers, and faculty members of medical education development centers, members of scientific committees, and faculty members who participated in Shahid Motahari Festival from 42 medical sciences universities in Iran. Data collection instruments were two reliable and valid questionnaires on the background and also participants' satisfaction towards Shahid Motahari Educational Festival. Data were analyzed using SPSS Software, version 14

Results: Among all participants, 30 FMs [6.3%] were educational deputies, 36 FMs [7.6%] managers of medical education development centers, 226 FMs [56.2%] members of scientific committees, 29 FMs [6.1%] members of the national committees, 343 FMs [27.5%] attendees, and 264 FMs [55.8%] had participated for retraining. The total satisfaction level of the participants was 73.3% which shows a good satisfaction level

Conclusion: The results identified the main important strength points such as "proposals' review process at the country level" and weakness points such as "organizing the festival"

[Concept analysis of occupational therapy handling in the children with cerebral palsy: a hybrid model]

Objective: This study aimed to analyze the concept of occupational therapy handling in the children with cerebral palsy from the perspective of occupational therapy instructors and clinicians in Iran

Materials and Methods: In this qualitative study, using hybrid model to clarify the concept of handling through three phases. For the theoretical phase, attributes of handling were recognized through a review of the literature [until February 2014], and six in-depth semi - structured interviews, two observations and one panel of experts were conducted for the fieldwork to develop attributes from the data and to verify those identified from the literature review. In the third phase attributes and final analysis of handling were extracted from the first and second phase

Results: The results were classified in five main categories that were identified as: [1] care of child, [2] management of treatment, [3] manual techniques, [4] education of activities of daily living [ADL], and [5] lifting and carrying. Core attributes of handling include [control, safety, transfer and positioning]

Conclusion: It seems that the results of this study may help in clarifying the concept of handling in children with CP. In addition, by identifying the process, barriers and facilitative factors, and the concept of handling, occupational therapy instructors and therapists will be able to design and run their educational activities based on scientific findings which can provide them with the necessary conditions for education, learning and proper execution of handling in occupational therapy

[Investigation of quality of life in mothers of children with spinabifida based on children's hoffer ambulatory criteria]

Objective: Mothers of children with spinabifida spend more time to care for their children. Doing this care, depending on the child's functional mobility level can probably cause damage to physical and mental health of mothers. This study aimed to determine the quality of life [QOL] of mothers of children with spinabifida [SB], according to the Hoffer levels using the SF-36 questionnaire

Materials and Methods: This research was a descriptive- analitical, cross-sectional study. The sample of this study was consisted of mothers of children with SB [2/5- 14 years old], in Tehran. The sample were selected by convenience sampling in the Rehabilitation Outpatient Clinics of University of Social Welfare and Rehabilitation Sciences, that 203 mothers were assessed in one clinic. Primery measures were the Hoffer criteria for grouping and determine the levels of ambulation in children with SB and the outcome measure was SF-36 questionnaire. Data were analyzed using, t test, ANOVA and MANOVA in SPSS [version 18]

Results: In this study, there were significant differences in mean scores on the physical component summary [PCS] [P<0/01] and Mental component summary [MCS] of SF36 [P<0/01] in mothers of children with SB in Hoffer levels. The significant difference in PCS and MCS of SF36, was related to the level I with the other levels of Hoffer criteria, there were no Significant difference in mean score for the PCS and MCS the QOL of mothers for sex and child's age levels [P<0/05]. There were a significant differences in mean PCS and MCS a QOL of mothers in different types of SB [P<0/01]. This significant difference was related to aculta with meningocele and myelomeningocele [P<0/01]

Conclusion: The dimensions of PCS and MCS of SF36 of mother with SB were affected with types of SB and increasing the levels of Hoffer. In conclusion, Mothers of children with SB require paying attention to their QOL during treatment of the child. In addition, the services should be created to support the physical and psychological aspects of the QOL

[ relationship between organizational citizenship behavior and organizational commitment in welfare staff [Tehran 2013]]

Objective: The purpose of this study was to investigate the relationship between organizational citizenship behavior, organizational commitment and its dimensions on the Welfare staff in Tehran 2013

Materials and Methods: In this cross - sectional study, one hundred eight staff of Tehran Welfare were selected by random sample, and the sample size of the previous studies. Data were collected using two standard questionnaires OCB, and Organizational Commitment, which includes the three dimensions, affective commitment, normative commitment and continuance commitment and analyzed by statistical methods such as: Pearson correlation coefficient and ANOVA

Results: The finding showed Between OCB and organizational commitment there was significant and positive correlation [P and le0.01, r=0.325]. Also the dimensions of organizational commitment: affective commitment and normative commitment have a significant positive relationship with OCB, but not significant relationship OCB with a continuous commitment. ANOVA results showed that the average OCB in age, type of employment and employee experience is different. And Continuous commitment in hiring employees is different and emotional commitment in Background employees is different

Conclusion: Based on the findings we conclude that the enhancement of organizational citizenship behavior, organizational commitment and staff of Tehran can be increased

[Study the relationship of executive functions with behavioral symptoms in children with high-functioning autism]

Objective: The relation between autism disorder's symptoms and cognitive capabilities can help with a better phenotype description of this disorder and can facilitate its pathological evaluation and treatment. Destruction of executive functions seems to be one of the cognitive reasons of potential phenotype in autism disorder. Thus, the present paper aims to study the relationship between executive dysfunction and autism disorder's symptoms

Materials and Methods: In this cross-sectional research, 50 children with high-functioning autism were selected using convenience sampling method from Behara, Tehranpars and Roshd centers. Then, the GARS test and Autism Spectrum Screening Questionnaire was completed by therapists and neuropsychological tests of Strop and continuous performance test and shift attention were taken by the subjects. Pearson correlation coefficient and multi-variant regression were used for data analysis

Results: There is a significant positive relationship between selective attention with communicative and social interaction symptoms, sustained attention with social interaction symptoms and repetitive behaviors, shifting attention with communicative, social interaction and repetitive behavior symptoms [P<0.001] [P<0.01] [P<0.05]. In addition, the results of regression analysis also revealed that selective attention and shifting attention can predict communication, and sustained attention can predict social interaction and repetitive behaviors symptoms [P<0.01] [P<0.05]

Conclusion: The results obtained by this study indicate the significant role of executive functions in autistic symptoms. Thus, it is recommended to consider new treatment interventions in repairing executive functions for treatment of children with autistic disorder

Independent and Social Living Skills Training for People with Schizophrenia in Iran: a Randomized Controlled Trial

Objectives: Schizophrenia is responsible for a significant proportion of burden of mental diseases in Iran. Lack of a follow-up system has resulted in the repeated hospitalizations. In this study it is hypothesized that standardized living skills training delivered to participants with schizophrenia in outpatient and inpatient centers can be effective compared to a control group [with occupational therapy] in reducing psychopathology severity and increasing quality of life.

Methods: This is a multi-centered parallel group randomized controlled trial in Iran and it is singleblinded. Eligible participants are randomly allocated into two groups in a 1:1 ratio. Participants are assigned by stratified balanced block randomization method. The trial is conducted in the cities of Tehran and Mashhad. Its aim is to recruit 160 clients with schizophrenia. The intervention for the experimental group is social living skills training. The intervention for the control group is occupational therapy. The intervention for both groups is conducted in 90 to 120-minute group sessions. The primary outcome of the study would be a decrease in psychopathology severity, an improvement in participants' quality of life, and reduction in family burden will be followed for 6 months.

Discussion: This paper presents a protocol for a randomized controlled trial of independent and social living skills training intervention delivered to participants with schizophrenia. If this intervention is effective, it could be scaled up to be developing for policymaking and improving outcomes for schizophrenic participants and their families in Iran.

Kinematic Analysis of Five Different Anterior Cruciate Ligament Reconstruction Techniques

Several anatomical anterior cruciate ligament (ACL) reconstruction techniques have been proposed to restore normal joint kinematics. However, the relative superiorities of these techniques with one another and traditional single-bundle reconstructions are unclear. Kinematic responses of five previously reported reconstruction techniques (single-bundle reconstruction using a bone-patellar tendon-bone graft [SBR-BPTB], single-bundle reconstruction using a hamstring tendon graft [SBR-HST], single-tunnel double-bundle reconstruction using a hamstring tendon graft [STDBR-HST], anatomical single-tunnel reconstruction using a hamstring tendon graft [ASTR-HST], and a double-tunnel double-bundle reconstruction using a hamstring tendon graft [DBR-HST]) were systematically analyzed. The knee kinematics were determined under anterior tibial load (134 N) and simulated quadriceps load (400 N) at 0degrees, 15degrees, 30degrees, 60degrees, and 90degrees of flexion using a robotic testing system. Anterior joint stability under anterior tibial load was qualified as normal for ASTR-HST and DBR-HST and nearly normal for SBR-BPTB, SBR-HST, and STDBR-HST as per the International Knee Documentation Committee knee examination form categorization. The analysis of this study also demonstrated that SBR-BPTB, STDBR-HST, ASTR-HST, and DBR-HST restored the anterior joint stability to normal condition while the SBR-HST resulted in a nearly normal anterior joint stability under the action of simulated quadriceps load. The medial-lateral translations were restored to normal level by all the reconstructions. The internal tibial rotations under the simulated muscle load were over-constrained by all the reconstruction techniques, and more so by the DBR-HST. All five ACL reconstruction techniques could provide either normal or nearly normal anterior joint stability; however, the techniques over-constrained internal tibial rotation under the simulated quadriceps load.

Vestibular stimulation and auditory perception in children with attention deficit hyperactivity disorder

Rehabilitation strategies play a pivotal role in reliving the inappropriate behaviors and improving children's performance during school. Concentration and visual and auditory comprehension in children are crucial to effective learning and have drawn interest from researchers and clinicians. Vestibular function deficits usually cause high level of alertness and vigilance, and problems in maintaining focus, paying selective attention, and altering in precision and attention to the stimulus. The aim of this study is to investigate the correlation between vestibular stimulation and auditory perception in children with attention deficit hyperactivity disorder. Totally 30 children aged from 7 to 12 years with attention deficit hyperactivity disorder participated in this study. They were assessed based on the criteria of diagnostic and statistical manual of mental disorders. After obtaining guardian and parental consent, they were enrolled and randomly matched on age to two groups of intervention and control. Integrated visual and auditory continuous performance test was carried out as a pre-test. Those in the intervention group received vestibular stimulation during the therapy sessions, twice a week for 10 weeks. At the end the test was done to both groups as post-test. The pre-and post-test scores were measured and compared the differences between means for two subject groups. Statistical analyses found a significant difference for the mean differences regarding auditory comprehension improvement. The findings suggest that vestibular training is a reliable and powerful option treatment for attention deficit hyperactivity disorder especially along with other trainings, meaning that stimulating the sense of balance highlights the importance of interaction between inhabitation and cognition

Standardization of connor-davidson resilience scale in Iranian subjects with cerebrovascular accident

Background: Resilience is a personal trait that can influence the stroke subjects' attitudes toward future opportunities and facilitate the transitional process and adaptation in them. Assessment of this trait in stroke subjects with a standardized tool would promote the rehabilitation protocols and occupational therapy interventions. Therefore, the objective of this study was to standardize the Connor-Davidson Resilience Scale [CD-RISC] for Persian Iranian people who have had strokes

Methods: A descriptive observational study was adopted in order to standardize the CD-RISC in stroke population. The population was comprised of 34 female and 29 male subjects with a mean age of 51.4 +/- 10.6 years and the history of ischemic or hemorrhagic cerebrovascular accidents. Subjects were recruited based on inclusion criteria within the period of two months between May and July of 2014. Descriptive statistics were calculated along with the Cronbach's alpha to determine reliability. Standard multiple regression analyses searched for any correlation between variables and resilience

Results: Statistical parameters revealed a mean of 58.4 +/- 15.5 for CD-RISC raw scores. Percentile ranks were also calculated from raw data. Cronbach's alpha of 0.892 revealed that the CD-RISC had high reliability for the population of this study. Multiple regression analyses showed that the functional status was the only variable that uniquely predicted subjects' resilience [beta=0.41; P<0.01]

Conclusion: The findings of this research confirmed applicability of CDRISC in Iranian people who have had strokes. The standardized CD-RISC was determined to be suitable for use in the clinic and for utilization in research studies in Iranian people status post-stroke