Proteus syndrome: a case report

The Proteus syndrome comprises an association of asymmetrical overgrowth of almost any part of the body, verrucous epidermal naevi, vascular malformations and lipoma-like subcutaneous hamartoma. Both sexes are affected with equal frequency and severity and it is not transmitted genetically. Here a 16-year-old man with asymmetric overgrowth of the extremities, macrodactyly, cerebriform hypertrophy of the soles and various skin and bony lesions is reported diagnosed as Proteus syndrome

Keratoderma palmoplantaris transgrediens [Mal de Meleda]: a case report

Mal de Meleda [keratoderma palmoplantaris transgrediens] is a rare autosomal recessive form of palmoplantar keratoderma with hyperkeratosis of palms and soles, which appears soon after birth and progressively involves other areas [transgrediens] of the skin especially dorsal aspects of hands and feet. We report a 20-year-old woman with Mal de Meleda with some unusual clinical features, i.e. peculiar finger nail anomalies and pseudoainhum on all her fingers