RESUMO
Caffeine is a well know substance with widely usage worldwide. Today some researches confirmed the conflicting effects of caffeine compound on cellular damage markers. The aim of this study was to determine the effect of different dosage of caffeine intake on some cellular damage markers in serum of male volleyball players after the one-single exhaustive resistance exercise. In a randomized double-blind design study, thirty elite male volleyball players [mean aged 21.47 +/- 1.45 years, fat percentage 10.47 +/- 3.11% and BMI 23.15 +/- 1.26 kg.m[2] were categorized to three equal groups: supplement groups [with 6 and 9 mg.kg[+1] caffeine] and placebo group [6 mg.kg[+1] dextrose]. After the supplementation, all subjects were participated in one-single-session of resistance weight-training [with 80% of one repetition maximum until exhaustive]. Changes in cellular damage indices [total serum CK, LDH and AST] were determined in three phases [Baseline, immediately and 24 hours after the training protocol]. The normal data were analyzed by repeated measure ANOVA and Bonferroni at alpha/=0.05]. Also, exhaustive resistance exercise significantly increased levels of 24-hour CK, LDH and AST in all groups [P/=0.05]. Based on the present findings, it could be concluded that acute intake of different doses of caffeine did not significantly prevent further damage- however it was not made the deterioration of the indirect indices of cell damage in compared with the placebo group