Outcomes of photorefractive keratectomy with intraoperative mitomycin-C

To report the efficacy, safety, predictability and complications of photo-refractive keratectomy [PRK] with intraoperative application of mitomycin-C [MMC]. This historical cohort study was performed on 1,250 eyes of 625 patients who underwent PRK using the Technolas 217 excimer laser machine by a single surgeon with intraoperative use of MMC 0.02% up to 2 minutes, depending on depth of ablation. A complete ophthalmologic examination was performed which included refraction, uncorrected visual acuity [UCVA], best-corrected visual acuity [BCVA] and slitlamp biomicroscopy. Outcomes were analyzed after one year of follow-up. The mean preoperative spherical equivalent refractive error was -4.85 +/- 2.27 [range, -2.50 to -13.5] diopters [D]. Mean depth of ablation was 89 +/- 22 microns and mean time to reepithelialization was 4.5 +/- 1.7 days. At final follow-up, UCVA of 20/20 and 20/40 or more was achieved in 92.1% and 99.2% of eyes, respectively. One year post-operatively, 69.4% and 91% of eyes were within +/- 0.50 D and +/- 1.00 D of emmetropia. Overall, 62 eyes [4.9%] developed one or two lines of decrease in BCVA, and 50 eyes [4%] developed corneal haze which was grade 1 or 2 in most cases; grade 3 and 4 corneal haze was found in 4 and 2 eyes, respectively. No other adverse event was noted during the study period. PRK with intraoperative application of MMC provides excellent visual outcomes with acceptable safety and predictability, and entails minimal side effects

Two years results of unilateral lateral rectus recession on moderate intermittent exotropia

This survey was performed to determine the effect of unilateral lateral rectus recession in treatment of moderate angle intermittent exotropia. However, this type of operation and its long term results in patients with moderate angle exotropia have not yet been studied in Iran. Forty patients with basic type intermittent exotropia with moderate angle deviation [25-30 delta D] were included in this study. All patients underwent unilateral lateral rectus recession [8 mm] in the relatively non-dominant eye. Patients were visited and examined after operation, 1 day, 1 week and 1 month later and then, every 6 months up to 3 years. Data were analyzed by t-paired test. Before operation all patients had 25-30delta D basic type intermittent exotropia. Two months after operation perfect orthophoria was observed in 33 [82.5%] subjects,