RESUMO
Abstract This study aimed to evaluate the effect of Bifidobacterium animalis subsp. lactis (B. lactis) HN019 in drinking water on the development of apical periodontitis (AP) in rats. In total 60 animals were divided into a control group (sound teeth); Group I - regular water without AP; Group II - probiotic water without AP; Group III - regular water with AP; Group IV - probiotic water with AP. AP was induced after 3 days in the control groups and after 7, 21, and 42 days in groups III and IV. The animals were euthanized, and the mandibles were subjected to histotechnical processing. Samples were stained with hematoxylin & eosin (H&E) to identify root canal features, apical and periapical regions. Additionally, histoenzymology was performed to detect osteoclasts, immunohistochemistry was used to identify osteoclastogenesis markers, and the Brown & Brenn technique was applied for microbiological analysis. The data were analyzed using GraphPad Prism 8.0.1 with a significance level of 5%. Although no statistical differences were observed, the groups administered with probiotics showed better conditions in terms of histological aspects seen microscopically. Furthermore, there were no differences in the number of osteoclasts (p > 0.05). The RANKL marker was not found in the probiotic group at 42 days, unlike in group III.
RESUMO
Objetivo: O presente estudo objetivou analisar a produção científica odontológica na área de saúde coletiva a partir de periódicos indexados na base de dados Scientific Eletronic Library Online (SciELO), sessão Saúde Pública. Materiais e Métodos: Foram analisados 10 periódicos, sessão Saúde Pública, com 605 números, totalizando 8.494 artigos científicos, indexados no SciELO e publicados entre janeiro de 1998 e dezembro de 2007. Resultados: Verificou-se que em relação à produção científica, das 8.494 publicações, 260 eram da área odontológica, correspondendo a 3% da produção analisada. A maior produção de artigos científicos concentrou-se no periódico Cadernos de Saúde Pública (26,5%) e a menor, na Revista de Salud Pública da Colômbia (2%). A maior parcela da produção científica originou-se de Instituições de Ensino Superior (48%). Dessas, 76,5% foi oriunda de instituições públicas localizadas, principalmente, no Sudeste do Brasil (54%). Conclusão: Foi possível observar, portanto, a crescente produção científica da área de saúde bucal coletiva brasileira, evidenciando-se uma maior concentração na região sudeste e uma grande participação das instituições de ensino superior.(AU)
Aim: This study aimed to analyze the dental scientific production in the area of Public Health, from periodicals indexed in the Scientific Electronic Library Online (SciELO) database. Materials and Methods: The present study analyzed 10 journals, in the area of public health, with 605 editions, totaling 8.494 articles, indexed in SciELO and published between January 1998 and December 2007. Results: Considering the total number of published articles (n=8.494), 260 were associated with dentistry, corresponding to 3% of the analyzed production. The largest scientific article production was concentrated in the Public Health Journals (26.5%), whereas a lesser amount could be found in the Revista de Salud Pública (Public Health Journal, Colombia) (2%). The great majority of scientific production came from institutions of higher education (48%), 76.5% of which came from public institutions, located mainly in the Southeastern regions of Brazil (54%). Conclusion: The results demonstrated the growth of scientific literature on public health in Brazil, but with obvious regional bias and prominent involvement of institutions of higher education.(AU)